Volociximab
Volociximab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against integrin alpha-5 and integrin beta-1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
No data
Clinical
Clinical Trials
16 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 2 | — | — | — | 2 |
| Renal cell carcinoma | D002292 | 1 | 1 | — | — | — | 2 | ||
| Melanoma | D008545 | — | 2 | — | — | — | 2 | ||
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | — | — | — | 2 | |
| Lung neoplasms | D008175 | C34.90 | — | 1 | — | — | — | 1 | |
| Peritoneal neoplasms | D010534 | — | 1 | — | — | — | 1 | ||
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fitness trackers | D000072936 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | VOLOCIXIMAB |
| INN | volociximab |
| Description | Volociximab (chimeric mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 558480-40-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108061 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB06647 |
| UNII ID | 496K5Z02NW (ChemIDplus, GSRS) |
Target
Agency Approved
ITGA5
ITGA5
ITGB1
ITGB1
Organism
Homo sapiens
Gene name
ITGA5
Gene synonyms
FNRA
NCBI Gene ID
Protein name
integrin alpha-5
Protein synonyms
CD49 antigen-like family member E, CD49e, Fibronectin receptor subunit alpha, fibronectin receptor, alpha polypeptide, fibronectin receptor, alpha subunit, Integrin alpha-F, integrin, alpha 5 (fibronectin receptor, alpha polypeptide), ITGA5/SLC9B1 fusion, very late activation protein 5, alpha subunit, VLA-5
Uniprot ID
Mouse ortholog
Itga5 (16402)
integrin alpha-5 (P11688)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 262 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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