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Vinpocetine
Vinpocetine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A and dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N06: Psychoanaleptics
— N06B: Psychostimulants, agents used for adhd and nootropics
— N06BX: Other psychostimulants and nootropics in atc
— N06BX18: Vinpocetine
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.9—11——1
InflammationD007249—11——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
EpilepsyD004827EFO_0000474G40.911———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVINPOCETINE
INNvinpocetine
Description
Vinpocetine is an alkaloid. It has a role as a geroprotector.
Classification
Small molecule
Drug classvinca alkaloids
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c(n1c1ccccc41)[C@@H]32
Identifiers
PDB—
CAS-ID42971-09-5
RxCUI24506
ChEMBL IDCHEMBL71752
ChEBI ID—
PubChem CID443955
DrugBankDB12131
UNII ID543512OBTC (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
PDE1A
PDE1A
PDE1C
PDE1C
Organism
Homo sapiens
Gene name
PDE1A
Gene synonyms
NCBI Gene ID
5136
Protein name
dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein synonyms
61 kDa Cam-PDE, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase, hCam-1, phosphodiesterase 1A, calmodulin-dependent
Uniprot ID
Q9UFX3
Mouse ortholog
Pde1a (18573)
dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Q9JLL9)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,438 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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50 adverse events reported
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