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Uracil mustard
Uracil mustard is a small molecule pharmaceutical. Uracil mustard was first approved as Uracil mustard on 1982-01-01. It is used to treat b-cell chronic lymphocytic leukemia, BCR-ABL positive chronic myelogenous leukemia, mycosis fungoides, ovarian neoplasms, and polycythemia vera amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
urogenital diseasesD000091642
hemic and lymphatic diseasesD006425
endocrine system diseasesD004700
immune system diseasesD007154
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Uracil mustard
Tradename
Company
Number
Date
Products
URACIL MUSTARDShireN-012892 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
b-cell chronic lymphocytic leukemiaD015451C91.1
bcr-abl positive chronic myelogenous leukemiaEFO_0000340D015464
mycosis fungoidesD009182C84.0
ovarian neoplasmsEFO_0003893D010051C56
polycythemia veraD011087D45
thrombocytosisD013922D75.83
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
L: Antineoplastic and immunomodulating agents
L01: Antineoplastic agents
L01A: Alkylating agents
L01AD: Nitrosoureas, antineoplastic alkylating agents
L01AD08: Uramustine
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameURACIL MUSTARD
INNuramustine
Description
5-[bis(2-chloroethyl)amino]uracil is a nitrogen mustard and an aminouracil.
Classification
Small molecule
Drug classuracil type antineoplastics
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Oc1ncc(N(CCCl)CCCl)c(O)n1
Identifiers
PDB
CAS-ID66-75-1
RxCUI10996
ChEMBL IDCHEMBL1488
ChEBI ID9884
PubChem CID6194
DrugBankDB00791
UNII IDW7KQ46GJ8U (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 147 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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