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Ulinastatin
Ulinastatin is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
B: Blood and blood forming organ drugs
— B02: Antihemorrhagics
— B02A: Antifibrinolytics
— B02AB: Proteinase inhibitors, antifibrinolytic
— B02AB05: Ulinastatin
HCPCS
No data
Clinical
Clinical Trials
26 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SepsisD018805A41.9——11—2
Cardiopulmonary bypassD002315———1—1
Septic shockD012772A48.3———1—1
Congenital heart defectsD006330HP_0001627Q24.9———1—1
Cardiovascular diseasesD002318EFO_0000319I98———1—1
PancreatitisD010195EFO_0000278K85———1—1
Coronary artery diseaseD003324I25.1———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StomatitisD013280EFO_1001904K12.1——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Respiratory distress syndromeD012128EFO_1000637J80—1——12
Covid-19D000086382U07.111———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Aortic dissectionD000784I71.0————22
HemostasisD006487————11
Acute kidney injuryD058186HP_0001919N17————11
Critical illnessD016638————11
Drug-related side effects and adverse reactionsD064420T88.7————11
Liver neoplasmsD008113EFO_1001513C22.0————11
InflammationD007249————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameULINASTATIN
INNulinastatin
Description
Ulinastatin, as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine or synthetically produced and has molecular weight of 25 - 40kDa. Highly purified ulinastatin has been clinically used for the treatment of acute pancreatitis, chronic pancreatitis, Stevens–Johnson syndrome, burns, septic shock, and toxic epidermal necrolysis (TEN).
Classification
Unknown
Drug classenzyme inhibitors: antihyperlipidemics (HMG-CoA inhibitors)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL2108163
ChEBI ID—
PubChem CID—
DrugBankDB12038
UNII IDOR3S9IF86U (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 1,631 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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25 adverse events reported
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