Ubidecarenone
Ubidecarenone is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
Trade Name
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Drug Products
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EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| angina pectoris | EFO_0003913 | D000787 | I20 |
| chronic fatigue syndrome | EFO_0004540 | D015673 | G93.31 |
| heart failure | EFO_0003144 | D006333 | I50 |
| huntington disease | Orphanet_399 | D006816 | G10 |
| hyperlipidemias | EFO_0003774 | D006949 | E78.5 |
| hypertension | EFO_0000537 | D006973 | I10 |
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
128 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 1 | 2 | 3 | 6 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | — | 1 | 1 | 1 | 3 |
| Renal dialysis | D006435 | EFO_0010690 | Z99.2 | — | — | — | 2 | 1 | 3 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | 1 | 1 | 2 |
| Myalgia | D063806 | HP_0003326 | M79.1 | — | — | — | 1 | 1 | 2 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | 2 | — | 2 |
| Traumatic brain injuries | D000070642 | S06 | — | — | — | 1 | — | 1 | |
| Dementia | D003704 | F03 | — | — | — | 1 | — | 1 | |
| Pseudobulbar palsy | D020828 | EFO_1001131 | — | — | — | 1 | — | 1 | |
| Muscle weakness | D018908 | HP_0001324 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 3 | 3 | — | — | 5 |
| Coronary artery disease | D003324 | I25.1 | — | 3 | 4 | — | — | 4 | |
| Progressive supranuclear palsy | D013494 | EFO_0002512 | G23.1 | — | 2 | 1 | — | 1 | 3 |
| Duchenne muscular dystrophy | D020388 | — | 2 | 2 | — | — | 3 | ||
| Chronic fatigue syndrome | D015673 | EFO_0004540 | G93.31 | — | 1 | 1 | — | 2 | 3 |
| Myelodysplastic syndromes | D009190 | D46 | 1 | 2 | 1 | — | — | 2 | |
| Pain | D010146 | EFO_0003843 | R52 | — | 1 | 1 | — | 1 | 2 |
| Huntington disease | D006816 | G10 | — | 1 | 1 | — | — | 2 | |
| Dyslipidemias | D050171 | HP_0003119 | — | — | 1 | — | — | 1 | |
| Nervous system diseases | D009422 | G00-G99 | — | 1 | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | 1 | 1 | — | — | — | 2 | |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 2 | — | — | — | 2 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | 1 | 1 | — | — | — | 2 |
| Squamous cell neoplasms | D018307 | 1 | 2 | — | — | — | 2 | ||
| Spinal cord injuries | D013119 | EFO_1001919 | — | 1 | — | — | — | 1 | |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.81 | — | 1 | — | — | — | 1 |
| Osteoporosis | D010024 | EFO_0003882 | M81.0 | — | 1 | — | — | — | 1 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 1 | — | — | — | 1 |
| Prader-willi syndrome | D011218 | Orphanet_739 | Q87.11 | — | 1 | — | — | — | 1 |
| Chronic renal insufficiency | D051436 | N18 | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 2 | — | — | — | 2 | 4 | ||
| Oxidative stress | D018384 | EFO_1001905 | 1 | — | — | — | 2 | 3 | |
| Neoplasms | D009369 | C80 | 2 | — | — | — | — | 2 | |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | — | — | — | — | 2 |
| Aging | D000375 | GO_0007568 | R41.81 | 1 | — | — | — | 1 | 2 |
| Fatigue | D005221 | HP_0012378 | R53.83 | 1 | — | — | — | 1 | 2 |
| Gliosarcoma | D018316 | 1 | — | — | — | — | 1 | ||
| Astrocytoma | D001254 | EFO_0000271 | 1 | — | — | — | — | 1 | |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 1 | — | — | — | — | 1 |
| Oral lichen planus | D017676 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Male infertility | D007248 | EFO_0004248 | N46 | — | — | — | — | 2 | 2 |
| Aneuploidy | D000782 | — | — | — | — | 2 | 2 | ||
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | — | — | 2 | 2 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | — | — | 1 | 1 |
| Dry eye syndromes | D015352 | H04.12 | — | — | — | — | 1 | 1 | |
| Autism spectrum disorder | D000067877 | F84.0 | — | — | — | — | 1 | 1 | |
| Migraine disorders | D008881 | EFO_0003821 | G43 | — | — | — | — | 1 | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | — | — | 1 | 1 |
| Cardiovascular abnormalities | D018376 | EFO_0003848 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | UBIDECARENONE |
| INN | ubidecarenone |
| Description | Coenzyme Q10 is a ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the E- configuration. It has a role as a human metabolite, a ferroptosis inhibitor and an antioxidant. |
| Classification | Small molecule |
| Drug class | aldosterone antagonists (spironolactone type) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | COC1=C(OC)C(=O)C(C/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C)=C(C)C1=O |
Identifiers
| PDB | — |
| CAS-ID | 303-98-0 |
| RxCUI | 21406 |
| ChEMBL ID | CHEMBL454801 |
| ChEBI ID | 46245 |
| PubChem CID | 5281915 |
| DrugBank | DB09270 |
| UNII ID | EJ27X76M46 (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 199 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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249 adverse events reported
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