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Tucidinostat
Tucidinostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against histone deacetylase 1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
150 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
T-cell lymphoma peripheralD016411C84.951531121
Breast neoplasmsD001943EFO_0003869C5041121216
T-cell lymphomaD016399—222—6
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Large b-cell lymphoma diffuseD016403C83.3—92—112
LeukemiaD007938C95—53——5
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.0—33——3
MelanomaD008545111—13
T-cell leukemiaD015458—22——2
B-cell leukemiaD015448—11——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-hodgkin lymphomaD008228C85.947———8
Non-small-cell lung carcinomaD00228916———6
Myeloid leukemia acuteD015470C92.035———6
Triple negative breast neoplasmsD064726—4——15
Healthy volunteers/patients—24———4
Hodgkin diseaseD006689C81—3———3
Multiple myelomaD009101C90.012———2
LymphomaD008223C85.9—1——12
NeoplasmsD009369C8012———2
Extranodal nk-t-cell lymphomaD054391C86.0—2———2
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeuroblastomaD009447EFO_00006211————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hemophagocytic lymphohistiocytosisD051359D76.1————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTUCIDINOSTAT
INNtucidinostat
Description
Chidamide is a member of benzamides.
Classification
Small molecule
Drug classenzyme inhibitors: histone deacetylase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)/C=C/c2cccnc2)cc1
Identifiers
PDB—
CAS-ID743420-02-2
RxCUI—
ChEMBL IDCHEMBL3621988
ChEBI ID—
PubChem CID12136798
DrugBankDB06334
UNII ID87CIC980Y0 (ChemIDplus, GSRS)
Target
Agency Approved
HDAC1
HDAC1
Organism
Homo sapiens
Gene name
HDAC1
Gene synonyms
RPD3L1
NCBI Gene ID
3065
Protein name
histone deacetylase 1
Protein synonyms
Protein deacetylase HDAC1, Protein decrotonylase HDAC1, reduced potassium dependency, yeast homolog-like 1
Uniprot ID
Q92534
Mouse ortholog
Hdac1 (433759)
histone deacetylase 1 (P97476)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 182 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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23 adverse events reported
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