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Troxerutin
Troxerutin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C05: Vasoprotectives
— C05C: Capillary stabilizing agents
— C05CA: Bioflavonoid drugs for capillary stabilizing
— C05CA04: Troxerutin
— C05CA54: Troxerutin, combinations
HCPCS
No data
Clinical
Clinical Trials
40 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—1——135
HemorrhoidsD006484EFO_0009552K64———2—2
Venous insufficiencyD014689———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ProctitisD011349EFO_0005628K62.89——1——1
Stable anginaD060050I20.8——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiovascular diseasesD002318EFO_0000319I98—1——12
Pediatric obesityD063766—1———1
Colorectal neoplasmsD015179—1———1
Alzheimer diseaseD000544EFO_0000249F03—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InflammationD0072491———23
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Metabolic syndromeD024821EFO_0000195E88.81————33
Appetitive behaviorD001070————22
FatigueD005221HP_0012378R53.83————22
Diet therapyD004035————11
ObesityD009765EFO_0001073E66.9————11
OverweightD050177E66.3————11
HypertensionD006973EFO_0000537I10————11
Varicose veinsD014648HP_0002619I83.90————11
SarcopeniaD055948EFO_1000653M62.84————11
Muscular dystrophiesD009136EFO_0000757G71.0————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTROXERUTIN
INNtroxerutin
Description
Troxerutin is a flavonol, a type of flavonoid, derived from rutin. It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the Japanese pagoda tree.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(-c4ccc(OCCO)c(OCCO)c4)oc4cc(OCCO)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
Identifiers
PDB—
CAS-ID56764-99-9
RxCUI—
ChEMBL IDCHEMBL3182320
ChEBI ID—
PubChem CID9896814
DrugBank—
UNII ID7Y4N11PXO8 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 735 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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85 adverse events reported
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