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Tranilast
Tranilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Allergic conjunctivitisD003233EFO_0007141H10.44———1—1
Percutaneous coronary interventionD062645———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PterygiumD011625H11.0——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.911———2
HyperuricemiaD033461—2———2
GoutD006073EFO_0004274M10—2———2
Cryopyrin-associated periodic syndromesD056587M04.2—1———1
NeoplasmsD009369C80—1———1
Nasopharyngeal neoplasmsD009303—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SarcoidosisD012507EFO_0000690D80-D891————1
Scleredema adultorumD0125921————1
MucinosesD0175201————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTRANILAST
INNtranilast
Description
Tranilast is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. It has a role as an anti-asthmatic drug, a nephroprotective agent, an anti-allergic agent, a calcium channel blocker, an antineoplastic agent, an aryl hydrocarbon receptor agonist and a hepatoprotective agent. It is a member of cinnamamides, a dimethoxybenzene, an amidobenzoic acid and a secondary carboxamide. It is functionally related to an anthranilic acid.
Classification
Small molecule
Drug classantiasthmatics/antiallergics (not acting primarily as antihistamines)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC
Identifiers
PDB—
CAS-ID53902-12-8
RxCUI57330
ChEMBL IDCHEMBL415324
ChEBI ID77572
PubChem CID5282230
DrugBankDB07615
UNII IDHVF50SMY6E (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,904 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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24 adverse events reported
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