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Tozadenant
Tozadenant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against adenosine receptor A2a.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lactose intoleranceD007787E73———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Parkinson diseaseD010300EFO_0002508G20—23——4
Chronic hepatitis bD019694EFO_0004197B18.1——2——2
LymphomaD008223C85.9——1——1
Hiv infectionsD015658EFO_0000764B20——1——1
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hepatic insufficiencyD0485501————1
Cocaine-related disordersD019970F141————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameTOZADENANT
INNtozadenant
Description
Tozadenant is a member of benzothiazoles.
Classification
Small molecule
Drug classadenosine receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1ccc(N2CCOCC2)c2sc(NC(=O)N3CCC(C)(O)CC3)nc12
Identifiers
PDB—
CAS-ID870070-55-6
RxCUI—
ChEMBL IDCHEMBL2105747
ChEBI ID—
PubChem CID—
DrugBankDB12203
UNII IDD9K857J81I (ChemIDplus, GSRS)
Target
Agency Approved
ADORA2A
ADORA2A
Organism
Homo sapiens
Gene name
ADORA2A
Gene synonyms
ADORA2
NCBI Gene ID
135
Protein name
adenosine receptor A2a
Protein synonyms
adenosine receptor subtype A2a
Uniprot ID
P29274
Mouse ortholog
Adora2a (11540)
adenosine receptor A2a (Q60613)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 123 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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