Toripalimab
Toripalimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
284 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 3 | — | 1 | 1 | 6 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 5 | 18 | 3 | — | 2 | 23 |
| Non-small-cell lung carcinoma | D002289 | 5 | 14 | 4 | — | — | 22 | ||
| Nasopharyngeal neoplasms | D009303 | 4 | 17 | 5 | — | — | 22 | ||
| Melanoma | D008545 | 8 | 7 | 1 | — | 2 | 16 | ||
| Squamous cell carcinoma of head and neck | D000077195 | 3 | 9 | 1 | — | — | 9 | ||
| Small cell lung carcinoma | D055752 | 1 | 5 | 1 | — | 1 | 7 | ||
| Cholangiocarcinoma | D018281 | C22.1 | — | 4 | 1 | — | 1 | 6 | |
| Urologic neoplasms | D014571 | C64-C68 | 3 | 3 | 1 | — | — | 6 | |
| Hepatocellular carcinoma | D006528 | C22.0 | 2 | 2 | 2 | — | — | 5 | |
| Triple negative breast neoplasms | D064726 | 1 | 2 | 2 | — | — | 5 |
Show 8 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | 26 | 17 | — | — | — | 32 | |
| Esophageal squamous cell carcinoma | D000077277 | 2 | 11 | — | — | — | 12 | ||
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 1 | 9 | — | — | 1 | 10 |
| Colorectal neoplasms | D015179 | 3 | 6 | — | — | 1 | 8 | ||
| Biliary tract neoplasms | D001661 | C24.9 | — | 5 | — | — | 1 | 6 | |
| Uterine cervical neoplasms | D002583 | 2 | 5 | — | — | — | 6 | ||
| Lung neoplasms | D008175 | C34.90 | 3 | 2 | — | — | 3 | 6 | |
| Adenocarcinoma | D000230 | 1 | 4 | — | — | — | 4 | ||
| Sarcoma | D012509 | — | 4 | — | — | — | 4 | ||
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 2 | 1 | — | — | — | 3 |
Show 25 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | C85.9 | 2 | — | — | — | — | 2 | |
| Induction chemotherapy | D060828 | 1 | — | — | — | — | 1 | ||
| Mouth neoplasms | D009062 | EFO_0003868 | C06.9 | 1 | — | — | — | — | 1 |
| Epstein-barr virus infections | D020031 | EFO_0000769 | 1 | — | — | — | — | 1 | |
| Liver transplantation | D016031 | EFO_0010682 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | TORIPALIMAB |
| INN | toripalimab |
| Description | Toripalimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | >6JBT:H|Heavy chain
QGQLVQSGAEVKKPGASVKVSCKASGYTFTDYEMHWVRQAPIHGLEWIGVIESETGGTAYNQKFKGRVTITADKSTSTAY
MELSSLRSEDTAVYYCAREGITTVATTYYWYFDVWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPE
PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRV
>6JBT:L|Light chain
DVVMTQSPLSLPVTLGQPASISCRSSQSIVHSNGNTYLEWYLQKPGQSPQLLIYKVSNRFSGVPDRFSGSGSGTDFTLKI
SRVEAEDVGVYYCFQGSHVPLTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQ
SGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |
Identifiers
| PDB | 6JBT |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297843 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 8JXN261VVA (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 1,747 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
20 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more