Temelimab
Temelimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target syncytin-1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
No data
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 2 | 3 | — | — | — | 5 |
| Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | 2 | — | — | — | 2 | |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 1 | — | — | — | 1 |
| Covid-19 | D000086382 | U07.1 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | TEMELIMAB |
| INN | temelimab |
| Description | Temelimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target syncytin-1. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4594547 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | T32CR1A69R (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ERVW-1
ERVW-1
Organism
Homo sapiens
Gene name
ERVW-1
Gene synonyms
ERVWE1
NCBI Gene ID
Protein name
syncytin-1
Protein synonyms
endogenous retroviral family W, env(C7), member 1, Endogenous retrovirus group W member 1, endogenous retrovirus group W, member 1, Env-W, envelope glycoprotein, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-tryptophan envelope protein, HERV-W Env glycoprotein, HERV-W envelope protein, HERV-W_7q21.2 provirus ancestral Env polyprotein, human endogenous retrovirus W envC7-1 envelope protein, Syncytin
Uniprot ID
Mouse ortholog
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Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 52 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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