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Sulprostone
Sulprostone is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target prostaglandin F2-alpha receptor, prostaglandin E2 receptor EP3 subtype, and prostaglandin E2 receptor EP1 subtype.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
G: Genito urinary system and sex hormones
G02: Other gynecologicals in atc
G02A: Uterotonics
G02AD: Prostaglandins, oxytocics
G02AD05: Sulprostone
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
No data
Indications Phases 1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Induced abortionD00002811
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSULPROSTONE
INNsulprostone
Description
Sulprostone is a prostanoid.
Classification
Small molecule
Drug classprostaglandins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CS(=O)(=O)NC(=O)CCC/C=C\C[C@H]1C(=O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)COc1ccccc1
Identifiers
PDB
CAS-ID60325-46-4
RxCUI
ChEMBL IDCHEMBL1472830
ChEBI ID
PubChem CID5312153
DrugBankDB12708
UNII ID501Q5EQ1GM (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
PTGFR
PTGFR
PTGER3
PTGER3
PTGER1
PTGER1
Organism
Homo sapiens
Gene name
PTGFR
Gene synonyms
NCBI Gene ID
Protein name
prostaglandin F2-alpha receptor
Protein synonyms
FP prostanoid receptor, PGF receptor, PGF2 alpha receptor, prostaglandin receptor (2-alpha), Prostanoid FP receptor
Uniprot ID
Mouse ortholog
Ptgfr (19220)
prostaglandin F2-alpha receptor (P43117)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 650 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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36 adverse events reported
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