Sulfamerazine
Lantrisul, Neotrizine, Sulfaloid, Sulfonamides Duplex, Sulfose, Terfonyl, Triple (sulfamerazine) is a small molecule pharmaceutical. Sulfamerazine was first approved as Sulfonamides duplex on 1982-01-01.
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Sulfamerazine
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SULFONAMIDES DUPLEX | Eli Lilly | N-006317 DISCN | 1982-01-01 | 1 products |
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Agency Specific
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ATC Codes
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06B: Chemotherapeutics for topical use
— D06BA: Sulfonamides, topical
— D06BA06: Sulfamerazine
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01E: Sulfonamides and trimethoprim antibacterials for systemic use
— J01ED: Long-acting sulfonamides
— J01ED07: Sulfamerazine
— J01EE: Combinations of sulfonamides and trimethoprim, incl. derivatives
— J01EE07: Sulfamerazine and trimethoprim
HCPCS
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Clinical
Clinical Trials
126 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malaria | D008288 | EFO_0001068 | B54 | 7 | 12 | 35 | 22 | 24 | 91 |
| Falciparum malaria | D016778 | EFO_0007444 | B50 | 1 | 5 | 8 | 4 | 8 | 23 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | 4 | 3 | 7 | 14 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | 5 | 1 | 4 | 10 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | 2 | 1 | 3 | 6 |
| Hiv | D006678 | O98.7 | 1 | — | — | 1 | — | 2 | |
| Treatment adherence and compliance | D000074822 | — | — | — | 1 | — | 1 | ||
| Pharmacokinetics | D010599 | — | — | — | 1 | — | 1 | ||
| Perinatal death | D066087 | HP_0003811 | — | — | — | 1 | — | 1 | |
| Stillbirth | D050497 | P95 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vivax malaria | D016780 | EFO_0007445 | B51 | — | 1 | 1 | — | 2 | 4 |
| Sickle cell anemia | D000755 | EFO_0000697 | D57 | 1 | 1 | 1 | — | — | 2 |
| Sexually transmitted diseases | D012749 | A50-A64 | — | — | 2 | — | — | 2 | |
| Asymptomatic diseases | D058070 | — | — | 1 | — | — | 1 | ||
| Respiratory tract infections | D012141 | J06.9 | — | — | 1 | — | — | 1 | |
| Premature birth | D047928 | EFO_0003917 | O60 | — | — | 1 | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | 1 | ||
| Bacterial vaginosis | D016585 | EFO_0003932 | — | — | 1 | — | — | 1 | |
| Trichomonas vaginitis | D014247 | EFO_0007521 | — | — | 1 | — | — | 1 | |
| Pneumocystis pneumonia | D011020 | EFO_0007448 | B59 | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cardiotoxicity | D066126 | EFO_1001482 | — | 1 | — | — | — | 1 | |
| Parasitemia | D018512 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoproliferative disorders | D008232 | Orphanet_2442 | D47.9 | 1 | — | — | — | — | 1 |
| Autoimmune diseases | D001327 | EFO_0000540 | M30-M36 | 1 | — | — | — | — | 1 |
| Therapeutic equivalency | D013810 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fever | D005334 | HP_0001945 | R50.9 | — | — | — | — | 1 | 1 |
| Birth weight | D001724 | EFO_0004344 | — | — | — | — | 1 | 1 | |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 | |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | — | — | 1 | 1 |
| Schistosomiasis | D012552 | EFO_1001475 | B65 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | SULFAMERAZINE |
| INN | sulfamerazine |
| Description | Sulfamerazine is a sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position. It has a role as an antiinfective agent and a drug allergen. It is a member of pyrimidines, a sulfonamide and a sulfonamide antibiotic. It is functionally related to a sulfanilamide. |
| Classification | Small molecule |
| Drug class | antimicrobials (sulfonamides derivatives) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1 |
Identifiers
| PDB | — |
| CAS-ID | 127-79-7 |
| RxCUI | 10176 |
| ChEMBL ID | CHEMBL438 |
| ChEBI ID | 102130 |
| PubChem CID | 5325 |
| DrugBank | DB01581 |
| UNII ID | UR1SAB295F (ChemIDplus, GSRS) |
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Safety
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255 adverse events reported
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