Simethicone-cellulose
Sonorx (simethicone-cellulose) is a small molecule pharmaceutical. Simethicone-cellulose was first approved as Sonorx on 1998-10-29. It is used to treat flatulence in the USA.
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Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| signs and symptoms pathological conditions | D013568 |
Trade Name
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Drug Products
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Simethicone-cellulose
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SONORX | Bracco Diagnostics | N-020773 DISCN | 1998-10-29 | 1 products |
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Agency Specific
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Clinical
Clinical Trials
43 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colonoscopy | D003113 | — | — | 1 | 4 | — | 5 | ||
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | 1 | — | — | 1 | 1 | 3 |
| Colic | D003085 | HP_0011848 | R10.83 | — | 1 | — | 1 | 1 | 3 |
| Diarrhea | D003967 | HP_0002014 | R19.7 | — | — | 1 | 1 | — | 2 |
| Colonic neoplasms | D003110 | C18 | — | — | — | 1 | 1 | 2 | |
| Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | — | 1 | — | 1 | |
| Chronic renal insufficiency | D051436 | N18 | — | — | — | 1 | — | 1 | |
| Colonic polyps | D003111 | K63.5 | — | — | — | 1 | — | 1 | |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | 1 | — | 1 |
| Ileus | D045823 | K56.7 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 1 | — | 3 | 4 | ||
| Female infertility | D007247 | EFO_0008560 | N97 | — | — | 1 | — | — | 1 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stomach diseases | D013272 | — | 1 | — | — | 1 | 2 | ||
| Otitis media | D010033 | EFO_0004992 | H66.9 | — | 1 | — | — | — | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | SIMETHICONE-CELLULOSE |
| INN | — |
| Description | Simeticone (INN), also known as simethicone (USAN), is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O |
Identifiers
| PDB | — |
| CAS-ID | 8050-81-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201493 |
| ChEBI ID | — |
| PubChem CID | 6433516 |
| DrugBank | DB09512 |
| UNII ID | — |
Target
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Variants
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Trends
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Safety
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Adverse Events
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1,380 adverse events reported
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