Senna
Senna is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Labels
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Brand Name | Status | Last Update |
|---|---|---|
| senna-s | OTC monograph not final | 2023-06-19 |
Indications
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Clinical
Clinical Trials
85 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Constipation | D003248 | HP_0002019 | K59.0 | — | 1 | 4 | 6 | 9 | 19 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | 2 | 2 | 4 |
| Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | — | 1 | — | 1 | — | 2 |
| Colorectal neoplasms | D015179 | — | — | — | 1 | 1 | 2 | ||
| Hypercholesterolemia | D006937 | HP_0003124 | — | — | — | 1 | 1 | 2 | |
| Dyslipidemias | D050171 | HP_0003119 | — | — | — | 1 | — | 1 | |
| Flushing | D005483 | R23.2 | — | — | — | 1 | — | 1 | |
| Neoplasms | D009369 | C80 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fecal incontinence | D005242 | R15 | — | 2 | 1 | — | 3 | 5 | |
| Dyspareunia | D004414 | HP_0030016 | N94.1 | 1 | — | 1 | — | — | 2 |
| Atrophy | D001284 | — | — | 1 | — | — | 1 | ||
| Menopause | D008593 | EFO_0003922 | N95 | — | — | 1 | — | — | 1 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | 1 | — | — | 1 |
| Dyspnea | D004417 | HP_0002094 | R06.0 | — | — | 1 | — | — | 1 |
| Rectal neoplasms | D012004 | — | — | 1 | — | — | 1 | ||
| Colonic neoplasms | D003110 | C18 | — | — | 1 | — | — | 1 | |
| Colonoscopy | D003113 | — | 1 | 1 | — | — | 1 | ||
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Male breast neoplasms | D018567 | 1 | 1 | — | — | — | 2 | ||
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 1 | — | — | 1 | 2 | |
| Healthy volunteers/patients | — | — | 1 | — | — | 1 | 2 | ||
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 1 | — | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | — | — | — | 1 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.81 | — | 1 | — | — | — | 1 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 1 | — | — | — | 1 |
| Gastroparesis | D018589 | EFO_1000948 | K31.84 | — | 1 | — | — | — | 1 |
| Gastrointestinal diseases | D005767 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | 1 | — | — | — | — | 1 |
| Urogenital abnormalities | D014564 | 1 | — | — | — | — | 1 | ||
| Dysuria | D053159 | EFO_0003901 | R30 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | — | — | 4 | 4 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | — | — | — | 3 | 3 |
| Renal dialysis | D006435 | EFO_0010690 | Z99.2 | — | — | — | — | 2 | 2 |
| Healthy diet | D000072001 | — | — | — | — | 2 | 2 | ||
| Necrotizing enterocolitis | D020345 | EFO_0003928 | K55.3 | — | — | — | — | 1 | 1 |
| Hirschsprung disease | D006627 | Q43.1 | — | — | — | — | 1 | 1 | |
| Colostomy | D003125 | — | — | — | — | 1 | 1 | ||
| Meconium ileus | D000074270 | P76.0 | — | — | — | — | 1 | 1 | |
| Encopresis | D004688 | F98.1 | — | — | — | — | 1 | 1 | |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | SENNA |
| INN | — |
| Description | Senna (senna) is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 128-57-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108558 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Trends
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Safety
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Adverse Events
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268,444 adverse events reported
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