Secobarbital
Seconal (secobarbital) is a small molecule pharmaceutical. Secobarbital was first approved as Seconal sodium on 1982-01-01. It is used to treat sleep initiation and maintenance disorders in the USA.
Download report
Favorite
Commercial
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Secobarbital sodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SECONAL SODIUM | Eli Lilly | N-007392 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| seconal sodium | 2007-05-31 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
95 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 6 | 1 | — | 1 | — | 8 | ||
| Vomiting | D014839 | HP_0002013 | R11.1 | — | — | — | 3 | 2 | 5 |
| Nausea | D009325 | HP_0002018 | R11.0 | — | — | — | 1 | 3 | 4 |
| Pain | D010146 | EFO_0003843 | R52 | — | 1 | — | 2 | — | 3 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | 1 | — | — | 1 | 1 | 3 |
| Colic | D003085 | HP_0011848 | R10.83 | — | 1 | — | 1 | — | 2 |
| Abdominal pain | D015746 | R10.9 | — | — | 1 | 1 | — | 2 | |
| Depression | D003863 | F33.9 | — | 1 | — | 1 | — | 2 | |
| First labor stage | D007747 | — | 1 | — | 1 | — | 2 | ||
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | 1 | — | 1 |
Show 5 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Motion sickness | D009041 | T75.3 | 2 | 3 | 6 | — | — | 9 | |
| Obstetric labor complications | D007744 | — | — | 2 | — | — | 2 | ||
| Acute abdomen | D000006 | R10.0 | — | — | 1 | — | — | 1 | |
| Labor pain | D048949 | — | 1 | 1 | — | — | 1 | ||
| Endoscopy | D004724 | — | 1 | 1 | — | — | 1 | ||
| Intestinal diseases | D007410 | HP_0002242 | K63.9 | — | — | 1 | — | — | 1 |
| Pancreatic diseases | D010182 | K86.9 | — | — | 1 | — | — | 1 | |
| Endoscopic retrograde cholangiopancreatography | D002760 | — | — | 1 | — | — | 1 | ||
| Bile duct diseases | D001649 | — | — | 1 | — | — | 1 | ||
| Pregnancy rate | D018873 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acute pain | D059787 | R52 | — | 1 | — | — | 1 | 2 | |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | 2 | — | — | — | 2 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 2 | — | — | — | 2 |
| Sialorrhea | D012798 | HP_0002307 | K11.7 | 1 | 1 | — | — | — | 1 |
| Gastrointestinal diseases | D005767 | — | 1 | — | — | — | 1 | ||
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | — | 1 | — | — | — | 1 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 1 | — | — | — | 1 |
| Endometrial neoplasms | D016889 | EFO_0004230 | 1 | 1 | — | — | — | 1 | |
| Obstetrical analgesia | D016362 | — | 1 | — | — | — | 1 | ||
| Mood disorders | D019964 | EFO_0004247 | F30-F39 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 3 | — | — | — | — | 3 |
| Dementia | D003704 | F03 | 2 | — | — | — | — | 2 | |
| Cognitive dysfunction | D060825 | G31.84 | 1 | — | — | — | 1 | 2 | |
| Hallucinations | D006212 | HP_0000738 | F06.0 | 1 | — | — | — | — | 1 |
| Psychotic disorders | D011618 | F20.81 | 1 | — | — | — | — | 1 | |
| Renal colic | D056844 | EFO_1001412 | N23 | 1 | — | — | — | — | 1 |
| Social phobia | D000072861 | EFO_1001917 | F40.1 | 1 | — | — | — | — | 1 |
| Memory disorders | D008569 | 1 | — | — | — | — | 1 | ||
| Epilepsy | D004827 | EFO_0000474 | G40.9 | 1 | — | — | — | — | 1 |
| Seizures | D012640 | G40.4 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | — | 1 | 1 | |
| Rhytidoplasty | D015361 | — | — | — | — | 1 | 1 | ||
| Dysmenorrhea | D004412 | HP_0100607 | N94.6 | — | — | — | — | 1 | 1 |
| Postoperative pain | D010149 | G89.18 | — | — | — | — | 1 | 1 | |
| Hysteroscopy | D015907 | — | — | — | — | 1 | 1 | ||
| Treatment-resistant depressive disorder | D061218 | — | — | — | — | 1 | 1 | ||
| Infertility | D007246 | EFO_0000545 | — | — | — | — | 1 | 1 | |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | — | 1 | 1 |
| Aids dementia complex | D015526 | EFO_0002608 | — | — | — | — | 1 | 1 | |
| Premature aging | D019588 | Orphanet_79389 | — | — | — | — | 1 | 1 |
Show 3 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | SECOBARBITAL |
| INN | secobarbital |
| Description | Secobarbital is a member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups. It has a role as an anaesthesia adjuvant, a GABA modulator and a sedative. It is functionally related to a barbituric acid. It is a conjugate acid of a secobarbital (1-). |
| Classification | Small molecule |
| Drug class | barbituric acid derivatives |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | C=CCC1(C(C)CCC)C(=O)NC(=O)NC1=O |
Identifiers
| PDB | — |
| CAS-ID | 76-73-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL447 |
| ChEBI ID | 9073 |
| PubChem CID | 5193 |
| DrugBank | DB00418 |
| UNII ID | 1P7H87IN75 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 1,122 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
3,512 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more