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Ronacaleret
Ronacaleret is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target extracellular calcium-sensing receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteoporosisD010024EFO_0003882M81.081———9
Fracture healingD017102—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Stem cell transplantationD0335811————1
Bone marrow transplantationD0160261————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRONACALERET
INNronacaleret
Description
Ronacaleret is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target extracellular calcium-sensing receptor.
Classification
Small molecule
Drug classcalcium receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cc(CCC(=O)O)cc(F)c1F
Identifiers
PDB—
CAS-ID753449-67-1
RxCUI—
ChEMBL IDCHEMBL1198855
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDDIH95YP7J3 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CASR
CASR
Organism
Homo sapiens
Gene name
CASR
Gene synonyms
GPRC2A, PCAR1
NCBI Gene ID
846
Protein name
extracellular calcium-sensing receptor
Protein synonyms
parathyroid Ca(2+)-sensing receptor 1, Parathyroid cell calcium-sensing receptor 1, PCaR1
Uniprot ID
Q4PJ19
Mouse ortholog
Casr (12374)
extracellular calcium-sensing receptor (Q9R1Y2)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 60 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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