Riviciclib
Riviciclib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against cyclin-dependent kinase 4, cyclin-dependent kinase 1, and cyclin-dependent kinase 9.
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Clinical
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11 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | C90.0 | 2 | 1 | — | — | — | 2 | |
| Squamous cell carcinoma of head and neck | D000077195 | 1 | 2 | — | — | — | 2 | ||
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | — | — | — | 1 |
| Head and neck neoplasms | D006258 | — | 1 | — | — | — | 1 | ||
| Mantle-cell lymphoma | D020522 | C83.1 | — | 1 | — | — | — | 1 | |
| Melanoma | D008545 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | 2 | — | — | — | — | 2 | |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
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Drug
General
| Drug common name | RIVICICLIB |
| INN | riviciclib |
| Description | Riviciclib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against cyclin-dependent kinase 4, cyclin-dependent kinase 1, and cyclin-dependent kinase 9. |
| Classification | Small molecule |
| Drug class | cyclin dependent kinase inhibitors (formerly-cidib) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CN1CCC(c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)C1CO |
Identifiers
| PDB | — |
| CAS-ID | 647019-54-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3545283 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 9EK26WE8QN (ChemIDplus, GSRS) |
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2 adverse events reported
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