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Rimexolone
Vexol (rimexolone) is a small molecule pharmaceutical. Rimexolone was first approved as Vexol on 1994-12-30. It is used to treat anterior uveitis and inflammation in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
eye diseasesD005128
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Rimexolone
Tradename
Company
Number
Date
Products
VEXOLEyevanceN-020474 DISCN1994-12-30
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
anterior uveitisEFO_1000811D014606—
inflammationMP_0001845D007249—
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
H: Systemic hormonal preparations, excl. sex hormones and insulins
— H02: Corticosteroids for systemic use
— H02A: Corticosteroids for systemic use, plain
— H02AB: Glucocorticoids, systemic
— H02AB12: Rimexolone
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01B: Antiinflammatory agents, ophthalmologic
— S01BA: Corticosteroid ophthalmologic antiinflammatory agents, plain
— S01BA13: Rimexolone
HCPCS
No data
Clinical
Clinical Trials
25 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic renal insufficiencyD051436N18—2—1—3
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
GoutD006073EFO_0004274M10—13——4
PericarditisD010493EFO_0007427I30—11——2
Cryopyrin-associated periodic syndromesD056587M04.2—11——2
Inborn genetic diseasesD030342EFO_0000508——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Familial mediterranean feverD010505M04.1—2———2
InflammationD007249—2———2
Juvenile arthritisD001171EFO_0002609M0811———2
Adult-onset still's diseaseD016706EFO_0007135M06.1—1———1
Alcoholic hepatitisD006519EFO_1001345K70.1—1———1
Cardiovascular diseasesD002318EFO_0000319I98—1———1
Systemic sclerodermaD012595EFO_0000717M3411———1
Diffuse sclerodermaD045743EFO_000040411———1
Schnitzler syndromeD019873EFO_1001165—1———1
AnemiaD000740EFO_0004272D64.9—1———1
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 1 diabetes mellitusD003922EFO_0001359E101————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRIMEXOLONE
INNrimexolone
Description
Rimexolone is a 20-oxo steroid.
Classification
Small molecule
Drug classsteroids (not prednisolone derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCC(=O)[C@@]1(C)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
Identifiers
PDB—
CAS-ID49697-38-3
RxCUI55681
ChEMBL IDCHEMBL1200617
ChEBI ID—
PubChem CID5311412
DrugBankDB00896
UNII IDO7M2E4264D (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 189 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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111 adverse events reported
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