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Refanezumab
Refanezumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target myelin-associated glycoprotein.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.911———2
Transient ischemic attackD002546EFO_0003764G45.9—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameREFANEZUMAB
INNrefanezumab
Description
Refanezumab (GSK249320) is a monoclonal antibody designed for the recovery of motor function after stroke.
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1233953-61-1
RxCUI—
ChEMBL IDCHEMBL3545317
ChEBI ID—
PubChem CID—
DrugBankDB14908
UNII ID3ZZ278643V (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
MAG
MAG
Organism
Homo sapiens
Gene name
MAG
Gene synonyms
GMA
NCBI Gene ID
4099
Protein name
myelin-associated glycoprotein
Protein synonyms
sialic acid binding Ig-like lectin 4A, sialic acid-binding immunoglobulin-like lectin 4A, Siglec-4a
Uniprot ID
P20916
Mouse ortholog
Mag (17136)
myelin-associated glycoprotein (P20917)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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