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Ravoxertinib
Ravoxertinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against mitogen-activated protein kinase 3 and mitogen-activated protein kinase 1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Mock data
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD0022891————1
NeoplasmsD009369C801————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRAVOXERTINIB
INNravoxertinib
Description
Ravoxertinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against mitogen-activated protein kinase 3 and mitogen-activated protein kinase 1.
Classification
Small molecule
Drug classtyrosine kinase inhibitors: epidermal growth factor receptor (EGFR) inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cn1nccc1Nc1nccc(-c2ccn([C@H](CO)c3ccc(Cl)c(F)c3)c(=O)c2)n1
Identifiers
PDB—
CAS-ID1453848-26-4
RxCUI—
ChEMBL IDCHEMBL3544964
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDR6AXV96CRH (ChemIDplus, GSRS)
Target
Agency Approved
MAPK3
MAPK3
MAPK1
MAPK1
Organism
Homo sapiens
Gene name
MAPK3
Gene synonyms
ERK1, PRKM3
NCBI Gene ID
5595
Protein name
mitogen-activated protein kinase 3
Protein synonyms
ERK-1, ERT2, Extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, MAPK 1, Microtubule-associated protein 2 kinase, p44-ERK1, p44-MAPK
Uniprot ID
P27361
Mouse ortholog
Mapk3 (26417)
mitogen-activated protein kinase 3 (Q91YW5)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 63 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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