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Ramatroban
Ramatroban is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target prostaglandin D2 receptor 2 and thromboxane A2 receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J45—11——1
Respiratory tract infectionsD012141J06.9—11——1
PneumoniaD011014EFO_0003106J18—11——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRAMATROBAN
INNramatroban
Description
Ramatroban is an organic molecular entity.
Classification
Small molecule
Drug classantithrombotics (thromboxane A2 receptor antagonists)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=C(O)CCn1c2c(c3ccccc31)C[C@H](NS(=O)(=O)c1ccc(F)cc1)CC2
Identifiers
PDB6IIU
CAS-ID116649-85-5
RxCUI—
ChEMBL IDCHEMBL361812
ChEBI ID—
PubChem CID123879
DrugBankDB13036
UNII IDP1ALI72U6C (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
PTGDR2
PTGDR2
TBXA2R
TBXA2R
Organism
Homo sapiens
Gene name
PTGDR2
Gene synonyms
CRTH2, DL1R, GPR44
NCBI Gene ID
11251
Protein name
prostaglandin D2 receptor 2
Protein synonyms
CD294, chemoattractant receptor homologous molecule expressed on T helper type 2 cells, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44, putative G-protein coupled receptor 44
Uniprot ID
Q9Y5Y4
Mouse ortholog
Ptgdr2 (14764)
prostaglandin D2 receptor 2 (Q9Z2J6)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 152 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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7 adverse events reported
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