Pyrantel
Pyrantel is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| ancylostomiasis | EFO_0007145 | D000724 | B76.0 |
| ascariasis | EFO_0007154 | D001196 | B77 |
| enterobiasis | — | D017229 | B80 |
| oesophagostomiasis | EFO_0007400 | D009814 | — |
| trichuriasis | EFO_0007524 | D014257 | B79 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hookworm infections | D006725 | EFO_0007314 | B76 | — | — | — | 1 | — | 1 |
| Trichuriasis | D014257 | EFO_0007524 | B79 | — | — | — | 1 | — | 1 |
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 3 | 3 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 | |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | — | — | 1 | 1 |
| Replacement arthroplasty knee | D019645 | — | — | — | — | 1 | 1 | ||
| Chronic pain | D059350 | HP_0012532 | — | — | — | — | 1 | 1 | |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PYRANTEL |
| INN | pyrantel |
| Description | Pyrantel is a carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'. It has a role as an antinematodal drug. It is a member of thiophenes, a carboxamidine and a member of 1,4,5,6-tetrahydropyrimidines. |
| Classification | Small molecule |
| Drug class | anthelmintics (undefined group) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CN1CCCN=C1/C=C/c1cccs1 |
Identifiers
| PDB | — |
| CAS-ID | 15686-83-6 |
| RxCUI | 8984 |
| ChEMBL ID | CHEMBL1626223 |
| ChEBI ID | 8654 |
| PubChem CID | 708857 |
| DrugBank | DB11156 |
| UNII ID | 4QIH0N49E7 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,416 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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16,363 adverse events reported
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