Praziquantel
Biltricide (praziquantel) is a small molecule pharmaceutical. Praziquantel was first approved as Biltricide on 1982-12-29. It is used to treat clonorchiasis, cysticercosis, helminthiasis, opisthorchiasis, and parasitic intestinal diseases amongst others in the USA.
Download report
Favorite
Commercial
Trade Name
FDA
EMA
Biltricide (generic drugs available since 2017-11-27)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Praziquantel
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| BILTRICIDE | Bayer | N-018714 RX | 1982-12-29 | 1 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| biltricide | New Drug Application | 2019-01-08 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| clonorchiasis | EFO_0007210 | D003003 | B66.1 |
| cysticercosis | EFO_0007231 | D003551 | B69 |
| helminthiasis | EFO_1001342 | D006373 | B65-B83 |
| opisthorchiasis | EFO_0007404 | D009889 | B66.0 |
| parasitic intestinal diseases | EFO_0009561 | D007411 | B82 |
| schistosomiasis | EFO_1001475 | D012552 | B65 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
41 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schistosomiasis | D012552 | EFO_1001475 | B65 | 1 | 4 | 4 | 2 | 5 | 15 |
| Schistosomiasis mansoni | D012555 | EFO_1001420 | B65.1 | — | 2 | — | 2 | 1 | 5 |
| Helminthiasis | D006373 | EFO_1001342 | B65-B83 | — | — | — | 1 | 3 | 4 |
| Malaria | D008288 | EFO_0001068 | B54 | — | — | — | 1 | 3 | 4 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | — | 1 | 2 | 3 |
| Hiv | D006678 | O98.7 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 5 | — | 1 | — | — | 6 | ||
| Schistosoma mansoni | D012550 | NCBITaxon_6183 | — | 1 | 3 | — | 1 | 4 | |
| Schistosoma haematobium | D012548 | — | 1 | 2 | — | — | 2 | ||
| Neurocysticercosis | D020019 | — | 1 | 2 | — | — | 2 | ||
| Schistosomiasis haematobia | D012553 | EFO_0007530 | B65.0 | — | — | 1 | — | — | 1 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | 1 | — | — | 1 |
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schistosomiasis japonica | D012554 | EFO_1001419 | B65.2 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Parasitic diseases | D010272 | EFO_0001067 | B88 | — | — | — | — | 2 | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | — | 2 | 2 |
| Taeniasis | D013622 | EFO_1001433 | B68 | — | — | — | — | 1 | 1 |
| Schistosoma | D012547 | — | — | — | — | 1 | 1 | ||
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 | |
| Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | — | — | 1 | 1 |
| Opportunistic infections | D009894 | — | — | — | — | 1 | 1 | ||
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 1 | 1 |
| Oxidative stress | D018384 | EFO_1001905 | — | — | — | — | 1 | 1 | |
| Hematuria | D006417 | HP_0000790 | R31 | — | — | — | — | 1 | 1 |
Show 1 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | PRAZIQUANTEL |
| INN | praziquantel |
| Description | 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one is a member of isoquinolines. |
| Classification | Small molecule |
| Drug class | anthelmintics (undefined group): 2-deoxoparaherquamide A derivatives |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3C2C1 |
Identifiers
| PDB | — |
| CAS-ID | 55268-74-1 |
| RxCUI | 8628 |
| ChEMBL ID | CHEMBL976 |
| ChEBI ID | — |
| PubChem CID | 4891 |
| DrugBank | DB01058 |
| UNII ID | 6490C9U457 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 8,909 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1,015 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more