Skip to content
Polivy(polatuzumab vedotin)
Polivy (polatuzumab vedotin) is an antibody pharmaceutical. Polatuzumab vedotin was first approved as Polivy on 2019-06-10. It is used to treat large b-cell lymphoma diffuse in the USA. It has been approved in Europe to treat b-cell lymphoma. The pharmaceutical is active against B-cell antigen receptor complex-associated protein beta chain.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
hemic and lymphatic diseasesD006425
immune system diseasesD007154
Trade Name
FDA
EMA
Polivy
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Polatuzumab vedotin
Tradename
Proper name
Company
Number
Date
Products
Polivypolatuzumab vedotin-piiqGenentechN-761121 RX2019-06-10
2 products
Labels
FDA
EMA
Brand Name
Status
Last Update
polivyBiologic Licensing Application2020-09-30
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
large b-cell lymphoma diffuseD016403C83.3
Agency Specific
FDA
EMA
Expiration
Code
polatuzumab vedotin, Polivy, Genentech, Inc.
2026-06-10Orphan excl.
Patent Expiration
No data
ATC Codes
L: Antineoplastic and immunomodulating agents
L01: Antineoplastic agents
L01F: Monoclonal antibodies and antibody drug conjugates
L01FX: Other monoclonal antibodies and antibody drug conjugates in atc
L01FX14: Polatuzumab vedotin
HCPCS
Code
Description
J9309
Injection, polatuzumab vedotin-piiq, 1 mg
Clinical
Clinical Trials
42 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Large b-cell lymphoma diffuseD016403C83.38114119
Non-hodgkin lymphomaD008228C85.987112
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
B-cell lymphomaD016393569
Follicular lymphomaD008224C82367
B-cell chronic lymphocytic leukemiaD015451C91.1123
Mantle-cell lymphomaD020522C83.1133
LymphomaD008223C85.9222
Reactive arthritisD016918EFO_0007460M02.3122
Hodgkin diseaseD006689C81122
Burkitt lymphomaD002051C83.7111
B-cell lymphoma marginal zoneD018442C88.411
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
RecurrenceD01200811
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common namePOLATUZUMAB VEDOTIN
INNpolatuzumab vedotin
Description
Polatuzumab vedotin (humanized mab)
Classification
Antibody
Drug classsynthetic analogs of the dolastatin series; monoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID1313206-42-6
RxCUI
ChEMBL IDCHEMBL3301582
ChEBI ID
PubChem CID
DrugBankDB12240
UNII IDKG6VO684Z6 (ChemIDplus, GSRS)
Target
Agency Approved
CD79B
CD79B
Organism
Homo sapiens
Gene name
CD79B
Gene synonyms
B29, IGB
NCBI Gene ID
Protein name
B-cell antigen receptor complex-associated protein beta chain
Protein synonyms
B-cell-specific glycoprotein B29, CD79b, CD79b antigen (immunoglobulin-associated beta), CD79b molecule, immunoglobulin-associated beta, Ig-beta, Immunoglobulin-associated B29 protein
Uniprot ID
Mouse ortholog
Cd79b (15985)
B-cell antigen receptor complex-associated protein beta chain (P15530)
Alternate
No data
Variants
Clinical Variant
No data
Financial
Polivy - Roche
$
£
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 1,097 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
505 adverse events reported
View more details