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Pixantrone dimaleate
Pixuvri (pixantrone dimaleate) is a small molecule pharmaceutical. Pixantrone dimaleate was first approved as Pixuvri on 2012-05-10. It has been approved in Europe to treat non-hodgkin lymphoma.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
hemic and lymphatic diseasesD006425
immune system diseasesD007154
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
L: Antineoplastic and immunomodulating agents
— L01: Antineoplastic agents
— L01D: Cytotoxic antibiotics and related substances
— L01DB: Anthracyclines and related substances
— L01DB11: Pixantrone
HCPCS
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-hodgkin lymphomaD008228C85.9213——6
LymphomaD008223C85.9211——4
Follicular lymphomaD008224C821—2——3
Large b-cell lymphoma diffuseD016403C83.3——1——1
LeukemiaD007938C95——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C50—1———1
Myeloid leukemia acuteD015470C92.011———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C802————2
B-cell chronic lymphocytic leukemiaD015451C91.11————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePIXANTRONE DIMALEATE
INNpixantrone
Description
Pixantrone is a member of isoquinolines.
Classification
Small molecule
Drug classantineoplastics, anthraquinone derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
NCCNc1ccc(NCCN)c2c1C(=O)c1ccncc1C2=O.O=C(O)/C=C\C(=O)O.O=C(O)/C=C\C(=O)O
Identifiers
PDB—
CAS-ID144510-96-3
RxCUI—
ChEMBL IDCHEMBL2103844
ChEBI ID—
PubChem CID134019
DrugBankDB06193
UNII IDF5SXN2KNMR (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 248 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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31 adverse events reported
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