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Piperacillin
Pipracil, Zosyn (piperacillin) is a small molecule pharmaceutical. Piperacillin was first approved as Pipracil on 1982-01-01. It is used to treat bacterial infections, escherichia coli infections, infectious skin diseases, intraabdominal infections, and pelvic infection amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
Combinations
Zosyn (generic drugs available since 2003-11-14)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Piperacillin sodium
Tradename
Company
Number
Date
Products
PIPRACILWYETH PHARMS INCN-050545 DISCN1982-01-01
4 products, RLD
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Piperacillin sodium
+
Tazobactam sodium
Tradename
Company
Number
Date
Products
ZOSYN IN PLASTIC CONTAINERBaxterN-050750 RX1998-02-24
3 products, RLD, RS
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
piperacillin and tazobactamANDA2023-04-25
zosynNew Drug Application2023-04-01
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infectionsD001424A49
escherichia coli infectionsEFO_1001318D004927B96.20
infectious skin diseasesD012874
intraabdominal infectionsD059413
pelvic infectionD034161
pneumoniaEFO_0003106D011014J18
proteus infectionsEFO_1001130D011512
pseudomonas infectionsEFO_0001076D011552
soft tissue infectionsD018461
streptococcal infectionsEFO_1001476D013290
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Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Piperacillin Sodium / Tazobactam Sodium, Zosyn, Wyeth Pharms
69001842023-04-14DPU-282
79152292023-04-14DP
81338832023-04-14DPU-282
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01C: Beta-lactam antibacterials, penicillins
J01CA: Penicillins with extended spectrum
J01CA12: Piperacillin
J01CR: Combinations of penicillins, incl. beta-lactamase inhibitors
J01CR05: Piperacillin and beta-lactamase inhibitor
HCPCS
Code
Description
J2543
Injection, piperacillin sodium/tazobactam sodium, 1 gram/0.125 grams (1.125 grams)
S0081
Injection, piperacillin sodium, 500 mg
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePIPERACILLIN
INNpiperacillin
Description
Piperacillin is a penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group. It has a role as an antibacterial drug. It is a penicillin and a penicillin allergen. It is a conjugate acid of a piperacillin(1-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCN1CCN(C(=O)N[C@@H](C(=O)N[C@@H]2C(=O)N3[C@@H](C(=O)O)C(C)(C)S[C@H]23)c2ccccc2)C(=O)C1=O
Identifiers
PDB
CAS-ID61477-96-1
RxCUI1546000
ChEMBL IDCHEMBL702
ChEBI ID8232
PubChem CID43672
DrugBankDB00319
UNII ID9I628532GX (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
Zosyn - Pfizer
$
£
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 33,788 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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14 adverse events reported
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