Penicillin v
Beepen-vk, Betapen-vk, Ledercillin, Pen-vee, Penapar-vk, Pfizerpen, Uticillin, V-cillin, Veetids (penicillin v) is a small molecule pharmaceutical. Penicillin v was first approved as V-cillin on 1982-01-01. It is used to treat bacillus anthracis, bacterial infections, diphtheria, gram-positive bacterial infections, and meningococcal meningitis amongst others in the USA.
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New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| penicillin v potassium | ANDA | 2023-06-14 |
| pfizerpen | ANDA | 2022-07-19 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| bacillus anthracis | NCBITaxon_1392 | D001408 | — |
| bacterial infections | — | D001424 | A49 |
| diphtheria | EFO_0005549 | D004165 | A36 |
| gram-positive bacterial infections | — | D016908 | — |
| meningococcal meningitis | EFO_1001040 | D008585 | A39.0 |
| pasteurella infections | EFO_0007424 | D010326 | A28.0 |
| pneumococcal infections | EFO_0000772 | D011008 | J13 |
Agency Specific
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
44 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syphilis | D013587 | EFO_0007504 | A53.9 | 1 | 2 | 2 | 5 | — | 9 |
| Tonsillitis | D014069 | HP_0011110 | J03 | — | — | — | 2 | 1 | 3 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | 1 | — | 2 | |
| Pharyngitis | D010612 | R07.0 | — | — | — | 1 | 1 | 2 | |
| Bacterial meningitis | D016920 | EFO_1000831 | G00 | — | — | — | 1 | — | 1 |
| Lyme disease | D008193 | A69.2 | — | — | — | 1 | — | 1 | |
| Erythema chronicum migrans | D015787 | A26.0 | — | — | — | 1 | — | 1 | |
| Communicable diseases | D003141 | — | — | — | 1 | — | 1 | ||
| Staphylococcus aureus | D013211 | NCBITaxon_1280 | — | — | — | 1 | — | 1 | |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | 2 | — | 1 | 3 |
| Sepsis | D018805 | A41.9 | — | — | 2 | — | — | 2 | |
| Yaws | D015001 | EFO_0007548 | A66 | — | — | 1 | — | — | 1 |
| Treponemal infections | D014211 | EFO_1001217 | — | — | 1 | — | — | 1 | |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | 1 | — | — | 1 |
| Microbial drug resistance | D004352 | — | — | 1 | — | — | 1 | ||
| Endocarditis | D004696 | EFO_0000465 | I33 | — | — | 1 | — | — | 1 |
| Bacterial infections | D001424 | A49 | — | — | 1 | — | — | 1 | |
| Neonatal sepsis | D000071074 | HP_0040187 | — | — | 1 | — | — | 1 | |
| Hiv | D006678 | O98.7 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rheumatic heart disease | D012214 | EFO_1001161 | I09.9 | — | 2 | — | — | 1 | 3 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | — | — | — | 1 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 3 | — | — | — | — | 3 | ||
| Oxidative stress | D018384 | EFO_1001905 | 1 | — | — | — | — | 1 | |
| Streptococcus agalactiae | D013292 | NCBITaxon_1311 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | — | 1 | 1 |
| Neurosyphilis | D009494 | EFO_0007339 | A50.4 | — | — | — | — | 1 | 1 |
| Peritonsillar abscess | D000039 | EFO_0007429 | J36 | — | — | — | — | 1 | 1 |
| Chorea | D002819 | EFO_0004152 | G25.5 | — | — | — | — | 1 | 1 |
| Streptococcal infections | D013290 | EFO_1001476 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PENICILLIN V |
| INN | phenoxymethylpenicillin |
| Description | Phenoxymethylpenicillin is a penicillin compound having a 6beta-(phenoxyacetyl)amino side-chain. It is a penicillin allergen and a penicillin. It is a conjugate acid of a phenoxymethylpenicillin(1-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 87-08-1 |
| RxCUI | 7984 |
| ChEMBL ID | CHEMBL615 |
| ChEBI ID | 27446 |
| PubChem CID | 6869 |
| DrugBank | DB00417 |
| UNII ID | Z61I075U2W (ChemIDplus, GSRS) |
Target
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Variants
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Safety
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Adverse Events
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38,172 adverse events reported
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