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Pemirolast
Alamast (pemirolast) is a small molecule pharmaceutical. Pemirolast was first approved as Alamast on 1999-09-24. It is used to treat allergic conjunctivitis in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
eye diseasesD005128
immune system diseasesD007154
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Pemirolast potassium
Tradename
Company
Number
Date
Products
ALAMASTSantenN-021079 DISCN1999-09-24
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
allergic conjunctivitisEFO_0007141D003233H10.44
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
19 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AnemiaD000740EFO_0004272D64.921151—19
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic renal insufficiencyD051436N18185——14
Chronic kidney failureD007676EFO_0003884N18.6184——13
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C8011———2
Pure red-cell aplasiaD012010HP_0012410—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePEMIROLAST
INNpemirolast
Description
Pemirolast is a pyridopyrimidine.
Classification
Small molecule
Drug classantiasthmatics/antiallergics (not acting primarily as antihistamines)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1cccn2c(=O)c(-c3nnn[nH]3)cnc12
Identifiers
PDB—
CAS-ID69372-19-6
RxCUI19551
ChEMBL IDCHEMBL1201198
ChEBI ID—
PubChem CID57697
DrugBankDB00885
UNII ID2C09NV773M (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 103 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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191 adverse events reported
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