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Pemetrexed, Pemfexy, Alimta, Armisarte, Pemetrexed Actavis (pemetrexed) is a small molecule pharmaceutical. Pemetrexed was first approved as Pemetrexed on 2004-09-20. It is used to treat mesothelial neoplasms and non-small-cell lung carcinoma in the USA. It has been approved in Europe to treat mesothelioma and non-small-cell lung carcinoma. The pharmaceutical is active against dihydrofolate reductase. In addition, it is known to target thymidylate synthase, proton-coupled folate transporter, and trifunctional purine biosynthetic protein adenosine-3. Alimta's patents are valid until 2035-10-28 (FDA).
Trade Name Alimta, Armisarte, Pemetrexed Actavis
Common Name Pemetrexed
Indication mesothelial neoplasms, mesothelioma, non-small-cell lung carcinoma
Drug Class Antineoplastic thymidylate synthetase inhibitors
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