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Patidegib
Patidegib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target protein smoothened; smoothened homolog.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Basal cell nevus syndromeD001478EFO_0004136123
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Basal cell neoplasmsD018295213
Pancreatic neoplasmsD010190EFO_0003860C25212
ChondrosarcomaD002813112
Primary myelofibrosisD055728D47.411
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Head and neck neoplasmsD00625811
AdenocarcinomaD00023011
NeoplasmsD009369C8011
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePATIDEGIB
INNpatidegib
Description
Patidegib is a member of piperidines.
Classification
Small molecule
Drug classhedgehog signaling inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC1=C2C[C@H]3[C@@H](CC[C@@H]4C[C@H](NS(C)(=O)=O)CC[C@]34C)[C@@H]2CC[C@@]2(C1)O[C@@H]1C[C@H](C)CN[C@H]1[C@H]2C
Identifiers
PDB
CAS-ID1037210-93-7
RxCUI
ChEMBL IDCHEMBL538867
ChEBI ID
PubChem CID25027363
DrugBankDB12655
UNII IDJT96FPU35X (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
SMO
SMO
Organism
Homo sapiens
Gene name
SMO
Gene synonyms
SMOH
NCBI Gene ID
Protein name
protein smoothened; smoothened homolog
Protein synonyms
frizzled family member 11, Protein Gx, seven transmembrane helix receptor, smoothened, frizzled family receptor, smoothened, seven transmembrane spanning receptor
Uniprot ID
Mouse ortholog
Smo (319757)
protein smoothened; smoothened homolog (P56726)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 37 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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