Skip to content
Pancrelipase
Creon, Pancreaze, Pertzye, Viokace, Zenpep (pancrelipase) is an enzyme pharmaceutical. Pancrelipase was first approved as Cotazym on 1996-12-09. It is used to treat exocrine pancreatic insufficiency in the USA.
Download report
Favorite
Top 200 Pharmaceuticals by Retail Sales
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
Trade Name
FDA
EMA
Creon, Pancreaze, Pertzye, Viokace, Zenpep (discontinued: Cotazym)
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Pancrelipase
Tradename
Proper name
Company
Number
Date
Products
CreonpancrelipaseAbbVieN-20725 RX2009-04-30
5 products
PertzyepancrelipaseDigestive CareN-22175 RX2012-05-17
4 products
PancreazepancrelipaseVivusN-22523 RX2010-04-12
6 products
ViokacepancrelipaseViokaceN-22542 RX2012-03-01
2 products
ZenpeppancrelipaseZenpepN-22210 RX2009-08-27
7 products
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
pancreazeBiologic Licensing Application2021-04-13
pertzyeBiologic Licensing Application2020-03-24
viokaceBiologic Licensing Application2020-03-23
zenpepBiologic Licensing Application2020-03-23
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
exocrine pancreatic insufficiency—D010188K86.81
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
52 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Multiple myelomaD009101C90.0331117
Non-hodgkin lymphomaD008228C85.914—116
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LymphomaD008223C85.9451——9
LeukemiaD007938C95332——8
MucositisD052016EFO_1001898214——6
StomatitisD013280EFO_1001904K12.1212——5
Head and neck neoplasmsD006258223——5
NeoplasmsD009369C80—12——3
Colonic neoplasmsD003110C18—11——1
PainD010146EFO_0003843R52——1——1
Squamous cell neoplasmsD018307——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myelodysplastic syndromesD009190D4624——16
Myeloid leukemia acuteD015470C92.012——14
Graft vs host diseaseD006086D89.8123——14
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.011——13
Bcr-abl positive chronic myelogenous leukemiaD015464EFO_0000340—2——13
Hodgkin diseaseD006689C8111——12
X-linked combined immunodeficiency diseasesD053632EFO_100145122———2
Plasma cell leukemiaD007952C90.111———1
Hematologic neoplasmsD019337—1———1
Non-small-cell lung carcinomaD002289—1———1
Show 7 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—1————1
Epidermolysis bullosaD004820Q811————1
Hematopoietic stem cell transplantationD0183801————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Primary myelofibrosisD055728D47.4————11
B-cell chronic lymphocytic leukemiaD015451C91.1————11
Myelomonocytic leukemia chronicD015477C93.1————11
Leukemia myeloid chronic atypical bcr-abl negativeD054438C92.2————11
B-cell lymphoma marginal zoneD018442C88.4————11
Follicular lymphomaD008224C82————11
Mantle-cell lymphomaD020522C83.1————11
Myeloid leukemia chronic-phaseD015466————11
Large b-cell lymphoma diffuseD016403C83.3————11
Myeloid leukemia accelerated phaseD015465————11
Show 5 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common namePANCRELIPASE
INN—
Description
Pancreatic enzymes, also known as pancreases or pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to certain pancreatic problems. These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long term pancreatitis, pancreatic cancer, or MODY 5, among others. The preparation is taken by mouth.
Classification
Enzyme
Drug classenzymes
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL2108074
ChEBI ID—
PubChem CID—
DrugBankDB00085
UNII ID—
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
Creon - Viatris
$
€
£
₣
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Creon - AbbVie
$
€
£
₣
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Zenpep - Allergan
$
€
£
₣
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Zenpep - Warner Chilcott
$
€
£
₣
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Pancreaze - Vivus
$
€
£
₣
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 785 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
464 adverse events reported
View more details