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Oxamniquine
Vansil (oxamniquine) is a small molecule pharmaceutical. Oxamniquine was first approved as Vansil on 1982-01-01. It is used to treat helminthiasis and schistosomiasis mansoni in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Oxamniquine
Tradename
Company
Number
Date
Products
VANSILMylanN-018069 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
helminthiasisEFO_1001342D006373B65-B83
schistosomiasis mansoniEFO_1001420D012555B65.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
— P02: Anthelmintics
— P02B: Antitrematodals
— P02BA: Quinoline derivatives and related substances, antitrematodals
— P02BA02: Oxamniquine
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
EndocarditisD004696EFO_0000465I33——11—2
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
BacteremiaD016470EFO_0003033R78.81—11——2
OsteomyelitisD010019EFO_0003102M86—11——2
Gram-positive bacterial infectionsD016908—11——2
Bacterial infectionsD001424A49——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOXAMNIQUINE
INNoxamniquine
Description
{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol is a member of the class of quinolines that is 1,2,3,4-tetrahydroquinoline which is substituted at positions 2, 6, and 7 by (isopropylamino)methyl, hydroxymethyl, and nitro groups, respectively. It is a member of quinolines, a C-nitro compound, a secondary amino compound and an aromatic primary alcohol.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)NCC1CCc2cc(CO)c([N+](=O)[O-])cc2N1
Identifiers
PDB—
CAS-ID21738-42-1
RxCUI7778
ChEMBL IDCHEMBL847
ChEBI ID78416
PubChem CID4612
DrugBankDB01096
UNII ID0O977R722D (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 607 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3,318 adverse events reported
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