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Moxalactam
Moxam (moxalactam) is a small molecule pharmaceutical. Moxalactam was first approved as Moxam on 1982-01-01. It is used to treat bacterial infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Moxalactam disodium
Tradename
Company
Number
Date
Products
MOXAMEli LillyN-050550 DISCN1982-01-01
5 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DD: Third-generation cephalosporins
— J01DD06: Latamoxef
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiovascular diseasesD002318EFO_0000319I98—12——3
Heart diseasesD006331EFO_0003777I51.9—12——3
Cardiac arrhythmiasD001145EFO_0004269I49.9—11——2
Ventricular tachycardiaD017180I47.2—11——2
Atrial fibrillationD001281EFO_0000275I48.0——1——1
Myocardial infarctionD009203EFO_0000612I21——1——1
Coronary diseaseD003327——1——1
Myocardial ischemiaD017202EFO_1001375I20-I25——1——1
Sudden death cardiacD016757EFO_0004278——1——1
Heart arrestD006323EFO_0009492I46——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMOXALACTAM
INNlatamoxef
Description
Moxalactam is a broad-spectrum oxacephem antibiotic in which the oxazine ring is substituted with a tetrazolylthiomethyl group and the azetidinone ring carries methoxy and 2-carboxy-2-(4-hydroxyphenyl)acetamido substituents. It has a role as an antibacterial drug. It is an oxacephem and a cephalosporin.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CO[C@@]1(NC(=O)C(C(=O)O)c2ccc(O)cc2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CO[C@@H]21
Identifiers
PDB—
CAS-ID64952-97-2
RxCUI7069
ChEMBL IDCHEMBL74632
ChEBI ID599928
PubChem CID47499
DrugBankDB04570
UNII IDVUF6C936Z3 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,353 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3 adverse events reported
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