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Moxalactam
Moxam (moxalactam) is a small molecule pharmaceutical. Moxalactam was first approved as Moxam on 1982-01-01. It is used to treat bacterial infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Moxalactam disodium
Tradename
Company
Number
Date
Products
MOXAMEli LillyN-050550 DISCN1982-01-01
5 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infectionsD001424A49
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01D: Other beta-lactam antibacterials in atc
J01DD: Third-generation cephalosporins
J01DD06: Latamoxef
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiovascular diseasesD002318EFO_0000319I98123
Heart diseasesD006331EFO_0003777I51.9123
Cardiac arrhythmiasD001145EFO_0004269I49.9112
Ventricular tachycardiaD017180I47.2112
Atrial fibrillationD001281EFO_0000275I48.011
Myocardial infarctionD009203EFO_0000612I2111
Coronary diseaseD00332711
Myocardial ischemiaD017202EFO_1001375I20-I2511
Sudden death cardiacD016757EFO_000427811
Heart arrestD006323EFO_0009492I4611
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMOXALACTAM
INNlatamoxef
Description
Moxalactam is a broad-spectrum oxacephem antibiotic in which the oxazine ring is substituted with a tetrazolylthiomethyl group and the azetidinone ring carries methoxy and 2-carboxy-2-(4-hydroxyphenyl)acetamido substituents. It has a role as an antibacterial drug. It is an oxacephem and a cephalosporin.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CO[C@@]1(NC(=O)C(C(=O)O)c2ccc(O)cc2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CO[C@@H]21
Identifiers
PDB
CAS-ID64952-97-2
RxCUI7069
ChEMBL IDCHEMBL74632
ChEBI ID599928
PubChem CID47499
DrugBankDB04570
UNII IDVUF6C936Z3 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,353 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3 adverse events reported
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