Molgramostim
Molgramostim is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Therapeutic Areas
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Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
355 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myeloid leukemia acute | D015470 | C92.0 | 3 | 7 | — | 1 | — | 10 | |
| Covid-19 | D000086382 | U07.1 | — | 4 | 1 | 1 | — | 5 | |
| Chronic hepatitis b | D019694 | EFO_0004197 | B18.1 | — | 1 | 1 | 1 | 1 | 4 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | C95 | 8 | 31 | 7 | — | 2 | 46 | |
| Lymphoma | D008223 | C85.9 | 8 | 31 | 4 | — | 1 | 43 | |
| Melanoma | D008545 | 8 | 29 | 3 | — | 1 | 39 | ||
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 17 | 20 | 2 | — | — | 33 |
| Neuroblastoma | D009447 | EFO_0000621 | 5 | 13 | 5 | — | 2 | 23 | |
| Myelodysplastic syndromes | D009190 | D46 | 8 | 13 | 1 | — | 1 | 22 | |
| Plasma cell neoplasms | D054219 | 5 | 12 | 1 | — | — | 17 | ||
| Hiv infections | D015658 | EFO_0000764 | B20 | 8 | 1 | 2 | — | 4 | 15 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 3 | 7 | 1 | — | — | 10 |
| Sarcoma | D012509 | 2 | 5 | 2 | — | — | 9 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | 7 | 15 | — | — | — | 20 | |
| Prostatic neoplasms | D011471 | C61 | 8 | 12 | — | — | — | 17 | |
| Lung neoplasms | D008175 | C34.90 | 6 | 7 | — | — | — | 13 | |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 6 | 7 | — | — | — | 12 |
| Colorectal neoplasms | D015179 | 3 | 9 | — | — | — | 10 | ||
| Multiple myeloma | D009101 | C90.0 | 3 | 5 | — | — | 1 | 9 | |
| Central nervous system neoplasms | D016543 | 3 | 6 | — | — | — | 9 | ||
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 3 | 7 | — | — | — | 8 |
| Fallopian tube neoplasms | D005185 | 4 | 3 | — | — | — | 7 | ||
| Male breast neoplasms | D018567 | 3 | 4 | — | — | — | 5 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Parkinson disease | D010300 | EFO_0002508 | G20 | 3 | — | — | — | — | 3 |
| Colonic neoplasms | D003110 | C18 | 2 | — | — | — | — | 2 | |
| Rectal neoplasms | D012004 | 2 | — | — | — | — | 2 | ||
| Kaposi sarcoma | D012514 | C46 | 2 | — | — | — | — | 2 | |
| Glioma | D005910 | EFO_0000520 | 2 | — | — | — | — | 2 | |
| Astrocytoma | D001254 | EFO_0000271 | 2 | — | — | — | — | 2 | |
| Oligodendroglioma | D009837 | EFO_0000631 | 2 | — | — | — | — | 2 | |
| Hepatocellular carcinoma | D006528 | C22.0 | 2 | — | — | — | — | 2 | |
| Small cell lung carcinoma | D055752 | 1 | — | — | — | — | 1 | ||
| Plasma cell leukemia | D007952 | C90.1 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Residual neoplasm | D018365 | — | — | — | — | 1 | 1 | ||
| Peripheral arterial disease | D058729 | EFO_0004265 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | MOLGRAMOSTIM |
| INN | molgramostim |
| Description | Molgramostim is a recombinant granulocyte macrophage colony-stimulating factor which functions as an immunostimulator.
|
| Classification | Protein |
| Drug class | colony-stimulating factors: granulocyte macrophage colony-stimulating factors (GM-CSF); colony-stimulating factors: macrophage colony-stimulating factors (M-CSF) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 99283-10-0 |
| RxCUI | 70161 |
| ChEMBL ID | CHEMBL2109134 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB12525 |
| UNII ID | B321AL142J (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Trends
PubMed Central
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Additional graphs summarizing 217 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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14 adverse events reported
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