Mivebresib
Mivebresib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target bromodomain-containing protein 4.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Primary myelofibrosis | D055728 | D47.4 | 1 | — | — | — | — | 1 | |
| Myeloid leukemia acute | D015470 | C92.0 | 1 | — | — | — | — | 1 | |
| Prostatic neoplasms | D011471 | C61 | 1 | — | — | — | — | 1 | |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
| Neoplasms | D009369 | C80 | 1 | — | — | — | — | 1 | |
| Non-small-cell lung carcinoma | D002289 | 1 | — | — | — | — | 1 | ||
| Non-hodgkin lymphoma | D008228 | C85.9 | 1 | — | — | — | — | 1 | |
| Multiple myeloma | D009101 | C90.0 | 1 | — | — | — | — | 1 | |
| Small cell lung carcinoma | D055752 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | MIVEBRESIB |
| INN | mivebresib |
| Description | Mivebresib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target bromodomain-containing protein 4. |
| Classification | Small molecule |
| Drug class | extra-terminal motif (BET) family of bromodomain (BRD) proteins |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 |
Identifiers
| PDB | — |
| CAS-ID | 1445993-26-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3987016 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | VR86R11J7J (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
BRD4
BRD4
Organism
Homo sapiens
Gene name
BRD4
Gene synonyms
HUNK1
NCBI Gene ID
Protein name
bromodomain-containing protein 4
Protein synonyms
chromosome-associated protein, female sterile homeotic related gene 4, mitotic chromosome-associated protein, Protein HUNK1
Uniprot ID
Mouse ortholog
Brd4 (57261)
bromodomain-containing protein 4 (Q9ESU6)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 122 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more