Skip to content
Methyltestosterone
Android, Metandren, Oreton, Testred, Virilon (methyltestosterone) is a small molecule pharmaceutical. Methyltestosterone was first approved as Metandren on 1982-01-01. It is used to treat breast neoplasms, delayed puberty, erectile dysfunction, and hypogonadism in the USA. The pharmaceutical is active against androgen receptor.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
endocrine system diseasesD004700
mental disordersD001523
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Methyltestosterone
Tradename
Company
Number
Date
Products
METANDRENNovartisN-003240 DISCN1982-01-01
4 products
ORETON METHYLMerck Sharp & DohmeN-003158 DISCN1982-01-01
2 products
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
esterified estrogens and methyltestosteroneunapproved drug other2023-04-21
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
breast neoplasmsEFO_0003869D001943C50
delayed pubertyHP_0000823D011628E30.0
erectile dysfunctionEFO_0004234D007172F52.21
hypogonadismHP_0000815D007006E23.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
G: Genito urinary system and sex hormones
G03: Sex hormones and modulators of the genital system
G03B: Androgens
G03BA: 3-oxoandrosten (4) derivatives
G03BA02: Methyltestosterone
G03E: Androgens and female sex hormones in combination
G03EA: Androgens and estrogens
G03EA01: Methyltestosterone and estrogen
G03EK: Androgens and female sex hormones in combination with other drugs
G03EK01: Methyltestosterone
HCPCS
No data
Clinical
Clinical Trials
16 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pre-eclampsiaD011225EFO_0000668O1412316
Pregnancy-induced hypertensionD046110O13213
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 1 diabetes mellitusD003922EFO_0001359E101113
HypertensionD006973EFO_0000537I101112
ProteinuriaD011507HP_0000093R80111
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Orthostatic intoleranceD05497122
Autonomic nervous system diseasesD001342EFO_0009532G9011
Orthostatic hypotensionD007024I95.111
Healthy volunteers/patients11
Postural orthostatic tachycardia syndromeD054972G90.A11
Chronic fatigue syndromeD015673EFO_0004540G93.3111
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameMETHYLTESTOSTERONE
INNmethyltestosterone
Description
Methyltestosterone is a 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position. It has a role as an antineoplastic agent, an anabolic agent and an androgen. It is a 3-oxo-Delta(4) steroid, a 17beta-hydroxy steroid and an enone. It is functionally related to a testosterone.
Classification
Small molecule
Drug classsteroids (androgens, anabolics); antiandrogens
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
Identifiers
PDB
CAS-ID58-18-4
RxCUI6904
ChEMBL IDCHEMBL1395
ChEBI ID27436
PubChem CID6010
DrugBankDB06710
UNII IDV9EFU16ZIF (ChemIDplus, GSRS)
Target
Agency Approved
AR
AR
Organism
Homo sapiens
Gene name
AR
Gene synonyms
DHTR, NR3C4
NCBI Gene ID
Protein name
androgen receptor
Protein synonyms
Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Uniprot ID
Mouse ortholog
Ar (11835)
androgen receptor (P19091)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 1,542 documents
View more details
Safety
Black-box Warning
Black-box warning for: Esterified estrogens and methyltestosterone
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
2,611 adverse events reported
View more details