Methocarbamol
Robaxin, Robaxisal (methocarbamol) is a small molecule pharmaceutical. Methocarbamol was first approved as Robaxisal on 1982-01-01. It is used to treat muscle cramp, muscle rigidity, myositis, pain, and spasm amongst others in the USA. It is known to target carbonic anhydrase 1.
Download report
Favorite
Commercial
Trade Name
FDA
EMA
Robaxin (generic drugs available since 1982-01-01, discontinued: Delaxin, Forbaxin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| methocarbamol | ANDA | 2023-06-07 |
| robaxin | New Drug Application | 2018-12-10 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| muscle cramp | HP_0003394 | D009120 | — |
| muscle rigidity | HP_0002063 | D009127 | — |
| myositis | EFO_0000783 | D009220 | G72.49 |
| pain | EFO_0003843 | D010146 | R52 |
| spasm | — | D013035 | M62.83 |
| tetanus | EFO_0005593 | D013742 | A35 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
— M03: Muscle relaxants
— M03B: Muscle relaxants, centrally acting agents
— M03BA: Carbamic acid esters, centrally acting muscle relaxants
— M03BA03: Methocarbamol
— M03BA53: Methocarbamol, combinations excl. psycholeptics
— M03BA73: Methocarbamol, combinations with psycholeptics
HCPCS
Code | Description |
|---|---|
| J2800 | Injection, methocarbamol, up to 10 ml |
Clinical
Clinical Trials
22 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Graves disease | D006111 | EFO_0004237 | E05.0 | 1 | 1 | 1 | 4 | 3 | 9 |
| Healthy volunteers/patients | — | — | — | — | 1 | — | 1 | ||
| Recurrence | D012008 | — | — | — | 1 | — | 1 | ||
| Therapeutics | D013812 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Graves ophthalmopathy | D049970 | EFO_1001466 | 1 | 1 | 1 | — | 1 | 3 | |
| Hyperthyroidism | D006980 | E05.9 | 1 | — | 1 | — | 1 | 3 | |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | 1 | 2 | — | — | — | 3 | |
| Dermatomyositis | D003882 | EFO_0000398 | M33 | — | 1 | — | — | — | 1 |
| Polymyositis | D017285 | EFO_0003063 | M33.2 | — | 1 | — | — | — | 1 |
| Glioma | D005910 | EFO_0000520 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanosis | D008548 | EFO_0003963 | L81.1 | 1 | — | — | — | — | 1 |
| Gliosarcoma | D018316 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Microbiota | D064307 | — | — | — | — | 2 | 2 | ||
| Gastrointestinal microbiome | D000069196 | — | — | — | — | 1 | 1 | ||
| Patient acceptance of health care | D010342 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | METHOCARBAMOL |
| INN | methocarbamol |
| Description | 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate is a carbamate ester that is glycerol in which one of the primary alcohol groups has been converted to its 2-methoxyphenyl ether while the other has been converted to the corresponding carbamate ester. It is a carbamate ester, a secondary alcohol and an aromatic ether. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | COc1ccccc1OCC(O)COC(N)=O |
Identifiers
| PDB | — |
| CAS-ID | 532-03-6 |
| RxCUI | 6845 |
| ChEMBL ID | CHEMBL1201117 |
| ChEBI ID | 77498 |
| PubChem CID | 4107 |
| DrugBank | DB00423 |
| UNII ID | 125OD7737X (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
CA1
CA1
Organism
Homo sapiens
Gene name
CA1
Gene synonyms
NCBI Gene ID
Protein name
carbonic anhydrase 1
Protein synonyms
CA-I, CAB, Carbonate dehydratase I, Carbonic anhydrase B, Carbonic anhydrase I, Cyanamide hydratase CA1, epididymis secretory protein Li 11, epididymis secretory sperm binding protein
Uniprot ID
Mouse ortholog
Car1 (12346)
carbonic anhydrase 1 (Q9DC84)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 716 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
2,223 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more