Pen-866
Pen-866 is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic ductal carcinoma | D021441 | 1 | 1 | — | — | — | 1 | ||
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | — | — | — | 1 |
| Neoplasms | D009369 | C80 | 1 | 1 | — | — | — | 1 | |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 1 | 1 | — | — | — | 1 |
| Endometrioid carcinoma | D018269 | 1 | 1 | — | — | — | 1 | ||
| Small cell lung carcinoma | D055752 | 1 | 1 | — | — | — | 1 | ||
| Adenocarcinoma | D000230 | 1 | 1 | — | — | — | 1 | ||
| Squamous cell carcinoma | D002294 | 1 | 1 | — | — | — | 1 | ||
| Squamous cell neoplasms | D018307 | 1 | 1 | — | — | — | 1 | ||
| Ewing sarcoma | D012512 | EFO_0000173 | 1 | 1 | — | — | — | 1 |
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Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PEN-866 |
| INN | locnartecan |
| Description | Pen-866 is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CCc1c2c(nc3ccc(OC(=O)N4CCC(CCn5ccc6cc(-n7c(-c8cc(C(C)C)c(O)cc8O)n[nH]c7=O)ccc65)CC4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC |
Identifiers
| PDB | — |
| CAS-ID | 1472614-83-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297475 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 56DL1J49LR (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 2 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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1 adverse events reported
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