Linrodostat
Linrodostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target indoleamine 2,3-dioxygenase 1.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
23 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | 5 | 5 | — | — | — | 7 | |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 1 | — | — | — | 1 |
| Endometrioid carcinoma | D018269 | — | 1 | — | — | — | 1 | ||
| Squamous cell carcinoma of head and neck | D000077195 | — | 1 | — | — | — | 1 | ||
| Squamous cell neoplasms | D018307 | — | 1 | — | — | — | 1 | ||
| Hepatocellular carcinoma | D006528 | C22.0 | 1 | 1 | — | — | — | 1 | |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 1 | — | — | — | 1 |
| Urinary bladder neoplasms | D001749 | C67 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 5 | — | — | — | — | 5 | ||
| Glioblastoma | D005909 | EFO_0000515 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | LINRODOSTAT |
| INN | linrodostat |
| Description | Linrodostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target indoleamine 2,3-dioxygenase 1. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors: indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H](C(=O)Nc1ccc(Cl)cc1)C1CCC(c2ccnc3ccc(F)cc23)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 1923833-60-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297598 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 0A7729F42K (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
IDO1
IDO1
Variants
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Trends
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Additional graphs summarizing 87 documents
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Safety
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Adverse Events
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58 adverse events reported
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