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Lanraplenib
Lanraplenib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target tyrosine-protein kinase SYK.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
5 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Membranous glomerulonephritisD015433EFO_0004254N03.211
Cutaneous lupus erythematosusD008178EFO_0003834L93.111
Sjogren's syndromeD012859EFO_0000699M35.011
Myeloid leukemia acuteD015470C92.0111
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLANRAPLENIB
INNlanraplenib
Description
Lanraplenib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target tyrosine-protein kinase SYK.
Classification
Small molecule
Drug classspleen tyrosine kinase (Syk) inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)n1
Identifiers
PDB
CAS-ID1800046-95-0
RxCUI
ChEMBL IDCHEMBL3986824
ChEBI ID
PubChem CID
DrugBank
UNII IDA6U64OU57E (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
SYK
SYK
Organism
Homo sapiens
Gene name
SYK
Gene synonyms
NCBI Gene ID
Protein name
tyrosine-protein kinase SYK
Protein synonyms
p72-Syk, Spleen tyrosine kinase
Uniprot ID
Mouse ortholog
Syk (20963)
tyrosine-protein kinase SYK (P48025)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 43 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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