Lactase
Lactase is an enzyme pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breath tests | D001944 | — | — | — | — | 1 | 1 | ||
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | LACTASE |
| INN | tilactase |
| Description | Lactase (EC 3.2.1.108) is an enzyme produced by many organisms. It is located in the brush border of the small intestine of humans and other mammals. It is essential to the complete digestion of whole milk; it breaks down lactose, a sugar which gives milk its sweetness. People who have deficiency of lactase, and consume dairy products, may experience the symptoms of lactose intolerance. Lactase can be purchased as a food supplement, and is added to milk to produce "lactose-free" milk products.
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| Classification | Enzyme |
| Drug class | enzymes |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | >4CKD:H,I,J,K|SCFV13R4 ANTIBODY FV HEAVY CHAIN
DVQLQESGPSLVKPSQTLSLTCSVTGDSITSDYWSWIRKFPGNRLEYMGYVSYSGSTYYNPSLKSRISITRDTSKNQYYL
DLNSVTTEDTATYYCANWDGDYWGQGTLVTVSAA
>4CKD:L,M,N,O|SCFV13R4 ANTIBODY FV LIGHT CHAIN
DIVLTQSPATLSVTPGNSVSLSCRASQSIGNDLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSGTDFTLSINSVET
EDFGMYFCQQSNSWPYTFGGGTKLEIK |
Identifiers
| PDB | 1JYN, 1JYV, 1JYW, 1JYX, 1JZ2, 1JZ3, 1JZ4, 1JZ5, 1JZ6, 1JZ7, 1JZ8, 1PX3, 1PX4, 1UWI, 1UWQ, 1UWR, 1UWS, 1UWT, 1UWU, 2CEQ, 3CZJ, 3E1F, 3J7H, 3OB8, 3OBA, 3SEP, 3T08, 3T09, 3T0A, 3T0B, 3T0D, 3T2O, 3T2P, 3T2Q, 3THC, 3VD3, 3VD4, 3VD5, 3VD7, 3VD9, 3VDA, 3VDB, 3VDC, 3WEZ, 3WF0, 3WF1, 3WF2, 3WF3, 3WF4, 4CKD, 4DUV, 4DUW, 4DUX, 4EAM, 4EAN, 4IUG, 4TTG, 4V44, 4V45, 5A1A, 5I3D, 5IFP, 5IFT, 5IHR, 5IXE, 5JUV, 5MGC, 5MGD, 6CVM, 6DRV, 6KUZ, 6S6Z, 6SD0, 6TSH, 6TSK, 6TTE, 6X1Q, 7BRS, 7BTK, 7KDV |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108505 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 37515NWH9U (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 7,706 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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69 adverse events reported
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