Isoetharine
Beta, Bronkometer, Bronkosol (isoetharine) is a small molecule pharmaceutical. Isoetharine was first approved as Bronkosol on 1982-01-01. It is used to treat asthma and bronchial spasm in the USA.
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Commercial
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| asthma | EFO_0000270 | D001249 | J45 |
| bronchial spasm | — | D001986 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
HCPCS
Code | Description |
|---|---|
| J7647 | Isoetharine hcl, inhalation solution, compounded product, administered through dme, concentrated form, per milligram |
| J7648 | Isoetharine hcl, inhalation solution, fda-approved final product, non-compounded, administered through dme, concentrated form, per milligram |
| J7649 | Isoetharine hcl, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram |
| J7650 | Isoetharine hcl, inhalation solution, compounded product, administered through dme, unit dose form, per milligram |
Clinical
Clinical Trials
105 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 3 | 10 | 16 | 16 | 17 | 62 |
| Asthma | D001249 | EFO_0000270 | J45 | 1 | 2 | 2 | 10 | 6 | 21 |
| Disease progression | D018450 | — | — | 1 | 3 | — | 4 | ||
| Dyspnea | D004417 | HP_0002094 | R06.0 | — | — | — | 1 | 2 | 3 |
| Pediatric obesity | D063766 | — | — | — | 1 | — | 1 | ||
| Cold temperature | D003080 | — | — | — | 1 | — | 1 | ||
| Exercise-induced asthma | D001250 | J45.990 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obstructive lung diseases | D008173 | HP_0006536 | — | 1 | 1 | — | — | 2 | |
| Pulmonary arterial hypertension | D000081029 | — | — | 1 | — | — | 1 | ||
| Familial dysautonomia | D004402 | Orphanet_1764 | G90.1 | — | — | 1 | — | — | 1 |
| Lung diseases | D008171 | EFO_0003818 | J98.4 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sialorrhea | D012798 | HP_0002307 | K11.7 | — | 1 | — | — | 1 | 2 |
| Respiratory insufficiency | D012131 | HP_0002093 | J96.9 | — | 1 | — | — | — | 1 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Common cold | D003139 | EFO_0007214 | J00 | — | — | — | — | 1 | 1 |
| Interstitial lung diseases | D017563 | EFO_0004244 | J84.89 | — | — | — | — | 1 | 1 |
| Exercise | D015444 | EFO_0000483 | — | — | — | — | 1 | 1 | |
| Quadriplegia | D011782 | HP_0002510 | G82.5 | — | — | — | — | 1 | 1 |
| Anesthesia | D000758 | — | — | — | — | 1 | 1 | ||
| Acute lung injury | D055371 | EFO_0004610 | — | — | — | — | 1 | 1 | |
| Thoracotomy | D013908 | — | — | — | — | 1 | 1 | ||
| Critical care | D003422 | — | — | — | — | 1 | 1 | ||
| Bronchitis | D001991 | J40 | — | — | — | — | 1 | 1 | |
| Bronchiectasis | D001987 | HP_0002110 | J47 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ISOETHARINE |
| INN | isoetarine |
| Description | Isoetharine is a catecholamine. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 |
Identifiers
| PDB | — |
| CAS-ID | 530-08-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201213 |
| ChEBI ID | 6005 |
| PubChem CID | 3762 |
| DrugBank | DB00221 |
| UNII ID | YV0SN3276Q (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
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Variants
Clinical Variant
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Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 200 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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21,502 adverse events reported
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