Irofulven
Irofulven is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Therapeutic Areas
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Trade Name
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
20 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | 2 | — | — | — | 2 | ||
| Prostatic neoplasms | D011471 | C61 | — | 1 | — | — | — | 1 | |
| Thyroid neoplasms | D013964 | EFO_0003841 | — | 1 | — | — | — | 1 | |
| Castration-resistant prostatic neoplasms | D064129 | — | 1 | — | — | — | 1 | ||
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 1 | — | — | — | 1 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 1 | — | — | — | 1 |
| Ovarian epithelial carcinoma | D000077216 | — | 1 | — | — | — | 1 | ||
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | — | — | — | 1 |
| Fallopian tube neoplasms | D005185 | — | 1 | — | — | — | 1 | ||
| Central nervous system neoplasms | D016543 | 1 | 1 | — | — | — | 1 |
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | IROFULVEN |
| INN | irofulven |
| Description | Irofulven is a member of cyclohexenones. |
| Classification | Small molecule |
| Drug class | antineoplastic, acylfulvene derivatives |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC1=C(CO)C2=C(C)C3(CC3)[C@@](C)(O)C(=O)C2=C1 |
Identifiers
| PDB | — |
| CAS-ID | 158440-71-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL118218 |
| ChEBI ID | — |
| PubChem CID | 148189 |
| DrugBank | DB05786 |
| UNII ID | 6B799IH05A (ChemIDplus, GSRS) |
Target
Agency Approved
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Variants
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Additional graphs summarizing 284 documents
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Safety
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Adverse Events
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13 adverse events reported
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