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Infergen(interferon alfacon-1)
Infergen (interferon alfacon-1) is a protein pharmaceutical. Interferon alfacon-1 was first approved as Infergen on 1997-10-06. It is used to treat brain neoplasms, chronic hepatitis c, colorectal neoplasms, cryoglobulinemia, and essential thrombocythemia amongst others in the USA. It has been approved in Europe to treat chronic hepatitis c.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
neoplasmsD009369
digestive system diseasesD004066
nervous system diseasesD009422
eye diseasesD005128
urogenital diseasesD000091642
cardiovascular diseasesD002318
hemic and lymphatic diseasesD006425
skin and connective tissue diseasesD017437
immune system diseasesD007154
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Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Interferon alfacon-1
Tradename
Proper name
Company
Number
Date
Products
Infergeninterferon alfacon-1SanofiN-103663 DISCN1997-10-06
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
brain neoplasmsEFO_0003833D001932C71
chronic hepatitis cEFO_0004220D019698B18.2
colorectal neoplasms—D015179—
cryoglobulinemiaEFO_0005846D003449D89.1
essential thrombocythemia—D013920D47.3
hairy cell leukemia—D007943C91.4
hemangioma—D006391D18.0
hepatitis dEFO_0007304D003699—
hepatocellular carcinoma—D006528C22.0
hypereosinophilic syndromeEFO_1001467D017681D72.11
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
L: Antineoplastic and immunomodulating agents
— L03: Immunostimulants
— L03A: Immunostimulants
— L03AB: Interferons
— L03AB09: Interferon alfacon-1
HCPCS
Code
Description
J9212
Injection, interferon alfacon-1, recombinant, 1 microgram
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hepatitis cD006526B19.2——1214
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic hepatitis cD019698EFO_0004220B18.2—13——4
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Human influenzaD007251EFO_0007328J11.111———1
Covid-19D000086382U07.1—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Renal cell carcinomaD0022921————1
Non-small-cell lung carcinomaD0022891————1
MelanomaD0085451————1
Liver neoplasmsD008113EFO_1001513C22.01————1
Colonic neoplasmsD003110C181————1
Neuroendocrine tumorsD018358EFO_1001901D3A.81————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameINTERFERON ALFACON-1
INNinterferon alfacon-1
Description
Interferon alpha-2 precursor (Interferon alpha-A) (LeIF A)
Classification
Protein
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID118390-30-0
RxCUI59744
ChEMBL IDCHEMBL1201557
ChEBI ID—
PubChem CID—
DrugBankDB00069
UNII ID56588OP40D (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 123 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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1,000 adverse events reported
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