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Indoximod
Indoximod is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
19 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C8051———5
GlioblastomaD005909EFO_000051532———4
Breast neoplasmsD001943EFO_0003869C5022——14
MelanomaD00854522———3
MedulloblastomaD00852721———3
EpendymomaD00480621———3
GliomaD005910EFO_000052021———2
GliosarcomaD01831621———2
Pancreatic neoplasmsD010190EFO_0003860C2521———2
Diffuse intrinsic pontine gliomaD00008044311———2
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—2————2
Non-small-cell lung carcinomaD0022891————1
Myeloid leukemia acuteD015470C92.01————1
Lung neoplasmsD008175C34.901————1
Brain neoplasmsD001932EFO_0003833C711————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameINDOXIMOD
INNindoximod
Description
1-methyltryptophan is a tryptophan derivative that is tryptophan carrying a single methyl substituent at position 1 on the indole. It has a role as an EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor and an antineoplastic agent. It is a non-proteinogenic alpha-amino acid and a tryptophan derivative.
Classification
Small molecule
Drug classimmunomodulators
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cn1cc(C[C@@H](N)C(=O)O)c2ccccc21
Identifiers
PDB—
CAS-ID110117-83-4
RxCUI—
ChEMBL IDCHEMBL571209
ChEBI ID—
PubChem CID98112
DrugBank—
UNII IDTX5CYN1KMZ (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 716 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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