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Indoximod
Indoximod is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
19 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C80515
GlioblastomaD005909EFO_0000515324
Breast neoplasmsD001943EFO_0003869C502214
MelanomaD008545223
MedulloblastomaD008527213
EpendymomaD004806213
GliomaD005910EFO_0000520212
GliosarcomaD018316212
Pancreatic neoplasmsD010190EFO_0003860C25212
Diffuse intrinsic pontine gliomaD000080443112
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
Non-small-cell lung carcinomaD00228911
Myeloid leukemia acuteD015470C92.011
Lung neoplasmsD008175C34.9011
Brain neoplasmsD001932EFO_0003833C7111
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameINDOXIMOD
INNindoximod
Description
1-methyltryptophan is a tryptophan derivative that is tryptophan carrying a single methyl substituent at position 1 on the indole. It has a role as an EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor and an antineoplastic agent. It is a non-proteinogenic alpha-amino acid and a tryptophan derivative.
Classification
Small molecule
Drug classimmunomodulators
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cn1cc(C[C@@H](N)C(=O)O)c2ccccc21
Identifiers
PDB
CAS-ID110117-83-4
RxCUI
ChEMBL IDCHEMBL571209
ChEBI ID
PubChem CID98112
DrugBank
UNII IDTX5CYN1KMZ (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 716 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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