Glycerin
Procalamine (glycerin) is a small molecule pharmaceutical. Glycerin was first approved as Procalamine on 1982-05-08. It is used to treat constipation and dermatitis in the USA.
Download report
Favorite
Searched
Commercial
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Amino acids
+
Calcium acetate
+
Glycerin
+
Magnesium acetate
+
Phosphoric acid
+
Potassium chloride
+
Sodium acetate
+
Sodium chloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| PROCALAMINE | B. Braun Medical | N-018582 DISCN | 1982-05-08 | 1 products |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| derma glide | unapproved drug other | 2023-06-15 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| constipation | HP_0002019 | D003248 | K59.0 |
| dermatitis | HP_0011123 | D003872 | L30.9 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A06: Drugs for constipation
— A06A: Drugs for constipation
— A06AG: Enema for constipation
— A06AG04: Glycerol
— A06AX: Other drugs for constipation in atc
— A06AX01: Glycerol
— A16: Other alimentary tract and metabolism products in atc
— A16A: Other alimentary tract and metabolism products in atc
— A16AX: Various alimentary tract and metabolism products
— A16AX09: Glycerol phenylbutyrate
HCPCS
No data
Clinical
Clinical Trials
93 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dry eye syndromes | D015352 | H04.12 | — | 2 | 2 | 4 | 5 | 11 | |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 1 | 1 | 1 | 2 | 5 |
| Keratoconjunctivitis sicca | D007638 | EFO_1000906 | — | — | — | 2 | 1 | 3 | |
| Pancreatitis | D010195 | EFO_0000278 | K85 | — | — | 1 | 1 | — | 2 |
| Dentin sensitivity | D003807 | — | — | — | 1 | 1 | 2 | ||
| Fibromyalgia | D005356 | EFO_0005687 | M79.1 | — | — | — | 1 | — | 1 |
| Abdominal obesity | D056128 | HP_0001956 | — | — | — | 1 | — | 1 | |
| Contact dermatitis | D003877 | L25 | — | — | — | 1 | — | 1 | |
| Occupational dermatitis | D009783 | — | — | — | 1 | — | 1 | ||
| Postoperative pain | D010149 | G89.18 | — | — | — | 1 | — | 1 |
Show 5 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemophilia b | D002836 | D67 | — | 1 | 1 | — | 1 | 2 | |
| Constipation | D003248 | HP_0002019 | K59.0 | — | 1 | 1 | — | — | 2 |
| Hygiene | D006920 | — | — | 2 | — | — | 2 | ||
| Bacterial meningitis | D016920 | EFO_1000831 | G00 | — | — | 1 | — | — | 1 |
| Rectal neoplasms | D012004 | — | — | 1 | — | — | 1 | ||
| Filarial elephantiasis | D004605 | EFO_0007272 | B74.0 | — | — | 1 | — | — | 1 |
| Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | — | — | 1 | — | — | 1 |
| Refractive errors | D012030 | EFO_0003908 | H52.7 | — | 1 | 1 | — | — | 1 |
| Proliferative vitreoretinopathy | D018630 | EFO_1001129 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | 3 | 4 |
| Food hypersensitivity | D005512 | EFO_1001890 | 1 | 2 | — | — | — | 2 | |
| Peanut hypersensitivity | D021183 | EFO_0007425 | 1 | 2 | — | — | — | 2 | |
| Hiv | D006678 | O98.7 | — | 1 | — | — | — | 1 | |
| Sarcoma | D012509 | — | 1 | — | — | — | 1 | ||
| Asthma | D001249 | EFO_0000270 | J45 | — | 1 | — | — | — | 1 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | 1 | 1 | — | — | — | 1 |
| Immediate hypersensitivity | D006969 | 1 | 1 | — | — | — | 1 | ||
| Headache disorders | D020773 | EFO_0009550 | G44 | 1 | 1 | — | — | — | 1 |
| Trigeminal neuralgia | D014277 | EFO_1001219 | G50.0 | 1 | 1 | — | — | — | 1 |
Show 2 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 2 | — | — | — | 2 | 4 | ||
| Parkinson disease | D010300 | EFO_0002508 | G20 | 1 | — | — | — | 1 | 2 |
| Epilepsy | D004827 | EFO_0000474 | G40.9 | 1 | — | — | — | — | 1 |
| Tympanosclerosis | D000092163 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Smoking | D012907 | EFO_0003768 | F17 | — | — | — | — | 2 | 2 |
| Xerostomia | D014987 | K11.7 | — | — | — | — | 2 | 2 | |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 1 | 1 |
| Hypoglycemia | D007003 | HP_0001943 | E16.2 | — | — | — | — | 1 | 1 |
| Hyperglycemia | D006943 | HP_0003074 | R73.9 | — | — | — | — | 1 | 1 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 1 | 1 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.81 | — | — | — | — | 1 | 1 |
| Insulin resistance | D007333 | EFO_0002614 | — | — | — | — | 1 | 1 | |
| Encopresis | D004688 | F98.1 | — | — | — | — | 1 | 1 | |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | — | — | — | — | 1 | 1 |
Show 16 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | GLYCERIN |
| INN | glycerol |
| Description | Glycerol is a triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups. It has a role as an osmolyte, a solvent, a detergent, a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite and a geroprotector. It is an alditol and a triol. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | OCC(O)CO |
Identifiers
| PDB | — |
| CAS-ID | 56-81-5 |
| RxCUI | 4910 |
| ChEMBL ID | CHEMBL692 |
| ChEBI ID | 17754 |
| PubChem CID | 753 |
| DrugBank | DB04077 |
| UNII ID | PDC6A3C0OX (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 470,884 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more