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Glucosamine
Glucosamine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target P2Y purinoceptor 14.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
musculoskeletal diseasesD009140
signs and symptoms pathological conditionsD013568
wounds and injuriesD014947
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
back painHP_0003418D001416M54
osteoarthritisEFO_0002506D010003M15-M19
sprains and strains—D013180—
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
— M01: Antiinflammatory and antirheumatic products
— M01A: Antiinflammatory and antirheumatic products, non-steroids
— M01AX: Other antiinflammatory and antirheumatic agents, non-steroids in atc
— M01AX05: Glucosamine
HCPCS
No data
Clinical
Clinical Trials
51 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Knee osteoarthritisD020370EFO_0004616M1711641022
OsteoarthritisD010003EFO_0002506M15-M19——42410
Oral lichen planusD017676———1—1
Back painD001416HP_0003418M54———1—1
Low back painD017116HP_0003419M54.5———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Irritable bowel syndromeD043183EFO_0000555K58—12——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ArthralgiaD018771HP_0002829M25.5—1——23
MalnutritionD044342EFO_0008572E40-E46—1———1
Breast neoplasmsD001943EFO_0003869C50—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.91————1
Insulin resistanceD007333EFO_00026141————1
Chronic periodontitisD055113EFO_0006343K05.31————1
Covid-19D000086382U07.11————1
CoronavirusD0179341————1
OverweightD050177E66.31————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Ankylosing spondylitisD013167EFO_0003898M45————11
Rheumatoid arthritisD001172EFO_0000685M06.9————11
InflammationD007249————11
Healthy volunteers/patients—————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameGLUCOSAMINE
INNglucosamine
Description
2-amino-2-deoxy-D-glucopyranose is a D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2. It has a role as an Escherichia coli metabolite, a mouse metabolite and a geroprotector. It is functionally related to a D-glucopyranose. It is a conjugate base of a 2-ammonio-2-deoxy-D-glucopyranose.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
Identifiers
PDB—
CAS-ID3416-24-8
RxCUI—
ChEMBL IDCHEMBL493287
ChEBI ID47977
PubChem CID439213
DrugBankDB01296
UNII IDN08U5BOQ1K (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
P2RY14
P2RY14
Organism
Homo sapiens
Gene name
P2RY14
Gene synonyms
GPR105, KIAA0001
NCBI Gene ID
9934
Protein name
P2Y purinoceptor 14
Protein synonyms
G protein coupled receptor for UDP-glucose, G-protein coupled receptor 105, P2Y(14) receptor, P2Y14 receptor, purinergic receptor P2Y, G-protein coupled, 14, UDP-glucose receptor
Uniprot ID
Q8IYT7
Mouse ortholog
P2ry14 (140795)
P2Y purinoceptor 14 (Q9ESG6)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 46,560 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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721 adverse events reported
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