Ganetespib
Ganetespib is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
38 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | 3 | 2 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 4 | — | — | 1 | 6 |
| Neoplasms | D009369 | C80 | 6 | 1 | — | — | — | 6 | |
| Fallopian tube neoplasms | D005185 | 2 | 3 | — | — | — | 3 | ||
| Triple negative breast neoplasms | D064726 | — | 2 | — | — | — | 2 | ||
| Rectal neoplasms | D012004 | 1 | 1 | — | — | — | 2 | ||
| Lung neoplasms | D008175 | C34.90 | 2 | 1 | — | — | — | 2 | |
| Prostatic neoplasms | D011471 | C61 | — | 2 | — | — | — | 2 | |
| Ovarian epithelial carcinoma | D000077216 | 2 | 2 | — | — | — | 2 | ||
| Myeloid leukemia acute | D015470 | C92.0 | 2 | 1 | — | — | — | 2 | |
| Small cell lung carcinoma | D055752 | 1 | 2 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | C90.0 | 1 | — | — | — | — | 1 | |
| Male breast neoplasms | D018567 | 1 | — | — | — | — | 1 | ||
| Esophageal neoplasms | D004938 | C15 | 1 | — | — | — | — | 1 | |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | — | — | — | — | 1 |
| Squamous cell carcinoma of head and neck | D000077195 | 1 | — | — | — | — | 1 | ||
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | C91.0 | 1 | — | — | — | — | 1 | |
| Myeloid leukemia chronic-phase | D015466 | 1 | — | — | — | — | 1 | ||
| Myeloproliferative disorders | D009196 | D47.1 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | GANETESPIB |
| INN | ganetespib |
| Description | Ganetespib is a member of triazoles and a ring assembly. |
| Classification | Small molecule |
| Drug class | heat shock protein inhibitors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3c(ccn3C)c2)c(O)cc1O |
Identifiers
| PDB | — |
| CAS-ID | 888216-25-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2103879 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB12047 |
| UNII ID | 2E8412Y946 (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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17 adverse events reported
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