Flumethasone pivalate
Locorten (flumethasone pivalate) is a small molecule pharmaceutical. Flumethasone pivalate was first approved as Locorten on 1982-01-01. It is used to treat atopic dermatitis, contact dermatitis, diaper rash, eczema, and otitis externa amongst others in the USA.
Download report
Favorite
Commercial
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Flumethasone pivalate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| LOCORTEN | Novartis | N-016379 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| atopic dermatitis | EFO_0000274 | D003876 | L20 |
| contact dermatitis | — | D003877 | L25 |
| diaper rash | — | D003963 | L22 |
| eczema | HP_0000964 | D004485 | L30.9 |
| otitis externa | EFO_0009560 | D010032 | H60 |
| otomycosis | — | D059249 | — |
| psoriasis | EFO_0000676 | D011565 | L40 |
| skin diseases | — | D012871 | L00-L99 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D07: Corticosteroids, dermatological preparations
— D07A: Corticosteroid dermatological preparations, plain
— D07AB: Corticosteroids, moderately potent (group ii)
— D07AB03: Flumetasone
— D07B: Corticosteroids, combinations with antiseptics
— D07BB: Corticosteroids, moderately potent, combinations with antiseptics
— D07BB01: Flumetasone and antiseptics
— D07C: Corticosteroids, combinations with antibiotics
— D07CB: Corticosteroids, moderately potent, combinations with antibiotics
— D07CB05: Flumetasone and antibiotics
— D07X: Corticosteroids, other combinations
— D07XB: Corticosteroids, moderately potent, other combinations
— D07XB01: Flumetasone
S: Sensory organ drugs
— S02: Otologicals
— S02C: Corticosteroids and antiinfectives in combination, otologic
— S02CA: Corticosteroids and antiinfectives in combination
— S02CA02: Flumetasone and antiinfectives
HCPCS
No data
Clinical
Clinical Trials
25 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cryptococcal meningitis | D016919 | EFO_0007228 | B45.1 | — | 4 | 2 | — | 7 | 12 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 2 | 1 | — | 5 | 8 |
| Glioblastoma | D005909 | EFO_0000515 | 4 | 2 | 1 | — | — | 5 | |
| Astrocytoma | D001254 | EFO_0000271 | 3 | 1 | 1 | — | — | 4 | |
| Oligodendroglioma | D009837 | EFO_0000631 | 2 | 1 | 1 | — | — | 3 | |
| Hiv | D006678 | O98.7 | — | 1 | 1 | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioma | D005910 | EFO_0000520 | 2 | — | — | — | — | 2 | |
| Gliosarcoma | D018316 | 2 | — | — | — | — | 2 | ||
| Gastrointestinal neoplasms | D005770 | C26.9 | 1 | — | — | — | — | 1 | |
| Urinary bladder neoplasms | D001749 | C67 | 1 | — | — | — | — | 1 | |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | FLUMETHASONE PIVALATE |
| INN | flumetasone |
| Description | Flumethasone is a fluorinated steroid, a glucocorticoid, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug. It derives from a hydride of a pregnane. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C(C)(C)C |
Identifiers
| PDB | — |
| CAS-ID | 2002-29-1 |
| RxCUI | 4458 |
| ChEMBL ID | CHEMBL1200877 |
| ChEBI ID | 31620 |
| PubChem CID | 16490 |
| DrugBank | DB00663 |
| UNII ID | LR3CD8SX89 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 107 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
470 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more